Cargando…

Association of Maternal Folate Intake and Offspring MTHFD1 and MTHFD2 Genes with Congenital Heart Disease

Existing evidence supported that congenital heart defect (CHD) was associated with a combination of environmental and genetic factors. Based on this, this study aimed at assessing the association of maternal folic acid supplementation (FAS), genetic variations in offspring methylenetetrahydrofolate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Hanjun, Ou, Jun, Chen, Yige, Chen, Qian, Luo, Manjun, Wang, Tingting, Qin, Jiabi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458540/ https://www.ncbi.nlm.nih.gov/pubmed/37630697 http://dx.doi.org/10.3390/nu15163502

Ejemplares similares

Association of Maternal Dietary Habits and MTHFD1 Gene Polymorphisms With Ventricular Septal Defects in Offspring: A Case-Control Study
por: Song, Xinli, et al.
Publicado: (2022)

Association of MTHFD1 gene polymorphisms and maternal smoking with risk of congenital heart disease: a hospital-based case-control study
por: Song, Xinli, et al.
Publicado: (2022)

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation
por: Sdelci, Sara, et al.
Publicado: (2019)

MTHFD2- a new twist?
por: Tedeschi, Philip M., et al.
Publicado: (2016)

The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation
por: Gustafsson Sheppard, Nina, et al.
Publicado: (2015)

MTHFD1L, A Folate Cycle Enzyme, Is Involved in Progression of Colorectal Cancer()()
por: Agarwal, Sumit, et al.
Publicado: (2019)

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells
por: Green, Alanna C., et al.
Publicado: (2023)

Targeting MTHFD2 in acute myeloid leukemia
por: Pikman, Yana, et al.
Publicado: (2016)

MTHFD1 controls DNA methylation in Arabidopsis
por: Groth, Martin, et al.
Publicado: (2016)

A Common Polymorphism in the MTHFD1 Gene Is a Modulator of Risk of Congenital Heart Disease
por: Karas Kuželički, Nataša, et al.
Publicado: (2022)

Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer
por: Nilsson, Roland, et al.
Publicado: (2014)

The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD
por: Fu, Chengzhang, et al.
Publicado: (2017)

The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation
por: Shang, Man, et al.
Publicado: (2021)

The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines
por: Wei, Yameng, et al.
Publicado: (2019)

Triglyceride regulate ACE2 level through MTHFD1
por: Ma, Xiaohua, et al.
Publicado: (2021)

The catalytic mechanism of the mitochondrial methylenetetrahydrofolate dehydrogenase/cyclohydrolase (MTHFD2)
por: Zhao, Li Na, et al.
Publicado: (2022)

Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism
por: Zhang, Fan, et al.
Publicado: (2022)

MTHFD2 facilitates breast cancer cell proliferation via the AKT signaling pathway
por: Huang, Jun, et al.
Publicado: (2021)

Independent and Interactive Influences of Environmental UVR, Vitamin D Levels, and Folate Variant MTHFD1-rs2236225 on Homocysteine Levels
por: Jones, Patrice, et al.
Publicado: (2020)

High expression of folate cycle enzyme MTHFD1L correlates with poor prognosis and increased proliferation and migration in colorectal cancer
por: He, Zhongyun, et al.
Publicado: (2020)

Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes
por: Yu, Chang, et al.
Publicado: (2019)

Distinct effects of folate pathway genes MTHFR and MTHFD1L on ruminative response style: a potential risk mechanism for depression
por: Eszlari, N, et al.
Publicado: (2016)

Non‐metabolic function of MTHFD2 activates CDK2 in bladder cancer
por: Liu, Xi, et al.
Publicado: (2021)

Binding Modes of Xanthine‐Derived Selective Allosteric Site Inhibitors of MTHFD2
por: Jha, Vibhu, et al.
Publicado: (2023)

Methylenetetrahydrofolate dehydrogenase (MTHFD) enzyme polymorphism as a maternal risk factor for trisomy 21: a clinical study
por: Neagos, D, et al.
Publicado: (2010)

Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy
por: Cheung, Chantal Hoi Yin, et al.
Publicado: (2019)

Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications
por: Ju, Huai-Qiang, et al.
Publicado: (2018)

PPFIA4 promotes castration-resistant prostate cancer by enhancing mitochondrial metabolism through MTHFD2
por: Zhao, Ru, et al.
Publicado: (2022)

Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells
por: Yue, Liang, et al.
Publicado: (2020)

Expression and Role of Methylenetetrahydrofolate Dehydrogenase 1 Like (MTHFD1L) in Bladder Cancer
por: Eich, Marie-Lisa, et al.
Publicado: (2019)

Protein interaction and functional data indicate MTHFD2 involvement in RNA processing and translation
por: Koufaris, Costas, et al.
Publicado: (2018)

Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2)
por: Lee, Lung-Chun, et al.
Publicado: (2021)

A redox probe screens MTHFD1 as a determinant of gemcitabine chemoresistance in cholangiocarcinoma
por: Pan, Ruogu, et al.
Publicado: (2021)

S295: TACROLIMUS MODULATES CD4+ T-CELL PROLIFERATION AND FUNCTION VIA MTHFD2 IN IMMUNE THROMBOCYTOPENIA
por: Yang, LI-Ping, et al.
Publicado: (2023)

Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell
por: Wan, Xingyou, et al.
Publicado: (2020)

Expression and Prognostic Value Identification of Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) in Brain Low-Grade Glioma
por: Shi, Lu-feng, et al.
Publicado: (2021)

The Prognostic Significance of Immune-Related Metabolic Enzyme MTHFD2 in Head and Neck Squamous Cell Carcinoma
por: Cui, Li, et al.
Publicado: (2020)

More Than a Metabolic Enzyme: MTHFD2 as a Novel Target for Anticancer Therapy?
por: Zhu, Zhiyuan, et al.
Publicado: (2020)

The Emerging Role of MTHFD Family Genes in Regulating the Tumor Immunity of Oral Squamous Cell Carcinoma
por: Wang, Wei, et al.
Publicado: (2022)

ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis
por: Gao, Yixing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0vtpmptvfe2n31kkuroud6rn44