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Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population

Introduction: The study was designed to evaluate the frequency of detection and the characteristics of subsolid nodules (SSNs) in outpatients’ chest computed tomography (CT) scans from a private hospital in Southern Brazil. Methods: A retrospective analysis of all chest CT scans was performed in adu...

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Autores principales: Zanardo, Ana Paula, Brentano, Vicente Bohrer, Grando, Rafael Domingos, Rambo, Rafael Ramos, Hertz, Felipe Teixeira, Anflor Junior, Luis Carlos, Prietto Dos Santos, Jonatas Favero, Galvao, Gabriela Schneider, Andrade, Cristiano Feijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458562/
https://www.ncbi.nlm.nih.gov/pubmed/37624112
http://dx.doi.org/10.3390/tomography9040119
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author Zanardo, Ana Paula
Brentano, Vicente Bohrer
Grando, Rafael Domingos
Rambo, Rafael Ramos
Hertz, Felipe Teixeira
Anflor Junior, Luis Carlos
Prietto Dos Santos, Jonatas Favero
Galvao, Gabriela Schneider
Andrade, Cristiano Feijo
author_facet Zanardo, Ana Paula
Brentano, Vicente Bohrer
Grando, Rafael Domingos
Rambo, Rafael Ramos
Hertz, Felipe Teixeira
Anflor Junior, Luis Carlos
Prietto Dos Santos, Jonatas Favero
Galvao, Gabriela Schneider
Andrade, Cristiano Feijo
author_sort Zanardo, Ana Paula
collection PubMed
description Introduction: The study was designed to evaluate the frequency of detection and the characteristics of subsolid nodules (SSNs) in outpatients’ chest computed tomography (CT) scans from a private hospital in Southern Brazil. Methods: A retrospective analysis of all chest CT scans was performed in adult patients from ambulatory care (non-lung cancer screening population) over a thirty-day period. Inclusion criteria were age > 18 years and lung-scanning protocols, including standard-dose high-resolution chest CT (HRCT), enhanced CT, CT angiography, and low-dose chest CT (LDCT). SSNs main features collected were mean diameter, number, density (pure or heterogenous ground glass nodules and part-solid), and localization. TheLungRADS system and the updated Fleischner Society’s pulmonary nodules recommendations were used for categorization only for study purposes, although not specifically fitting the population. The presence of emphysema, as well as calcified and solid nodules were also addressed. Statistical analysis was performed using R software, categorial variables are shown as absolute or relative frequencies, and continuous variables as mean and interquartile ranges. Results: Chest computed tomography were performed in 756 patients during the study period (September 2019), and 650 met the inclusion criteria. The IQR for age was 53/73 years; most participants were female (58.3%) and 10.6% had subsolid nodules detected. Conclusions: The frequency of SSNs detection in patients in daily clinical practice, not related to screening populations, is not negligible. Regardless of the final etiology, follow-up is often indicated, given the likelihood of malignancy for persistent lesions.
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spelling pubmed-104585622023-08-27 Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population Zanardo, Ana Paula Brentano, Vicente Bohrer Grando, Rafael Domingos Rambo, Rafael Ramos Hertz, Felipe Teixeira Anflor Junior, Luis Carlos Prietto Dos Santos, Jonatas Favero Galvao, Gabriela Schneider Andrade, Cristiano Feijo Tomography Communication Introduction: The study was designed to evaluate the frequency of detection and the characteristics of subsolid nodules (SSNs) in outpatients’ chest computed tomography (CT) scans from a private hospital in Southern Brazil. Methods: A retrospective analysis of all chest CT scans was performed in adult patients from ambulatory care (non-lung cancer screening population) over a thirty-day period. Inclusion criteria were age > 18 years and lung-scanning protocols, including standard-dose high-resolution chest CT (HRCT), enhanced CT, CT angiography, and low-dose chest CT (LDCT). SSNs main features collected were mean diameter, number, density (pure or heterogenous ground glass nodules and part-solid), and localization. TheLungRADS system and the updated Fleischner Society’s pulmonary nodules recommendations were used for categorization only for study purposes, although not specifically fitting the population. The presence of emphysema, as well as calcified and solid nodules were also addressed. Statistical analysis was performed using R software, categorial variables are shown as absolute or relative frequencies, and continuous variables as mean and interquartile ranges. Results: Chest computed tomography were performed in 756 patients during the study period (September 2019), and 650 met the inclusion criteria. The IQR for age was 53/73 years; most participants were female (58.3%) and 10.6% had subsolid nodules detected. Conclusions: The frequency of SSNs detection in patients in daily clinical practice, not related to screening populations, is not negligible. Regardless of the final etiology, follow-up is often indicated, given the likelihood of malignancy for persistent lesions. MDPI 2023-08-09 /pmc/articles/PMC10458562/ /pubmed/37624112 http://dx.doi.org/10.3390/tomography9040119 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Zanardo, Ana Paula
Brentano, Vicente Bohrer
Grando, Rafael Domingos
Rambo, Rafael Ramos
Hertz, Felipe Teixeira
Anflor Junior, Luis Carlos
Prietto Dos Santos, Jonatas Favero
Galvao, Gabriela Schneider
Andrade, Cristiano Feijo
Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population
title Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population
title_full Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population
title_fullStr Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population
title_full_unstemmed Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population
title_short Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population
title_sort retrospective analysis of subsolid nodules’ frequency using chest computed tomography detection in an outpatient population
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458562/
https://www.ncbi.nlm.nih.gov/pubmed/37624112
http://dx.doi.org/10.3390/tomography9040119
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