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Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain

Zoonotic leishmaniasis caused by Leishmania infantum is distributed worldwide and affects humans and domestic and wild mammals. In Europe, specifically in the Mediterranean basin, leishmaniasis is endemic due to the concurrence of the phlebotomine vectors and reservoir mammals, including carnivorous...

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Autores principales: Azami-Conesa, Iris, Pérez-Moreno, Paula, Matas Méndez, Pablo, Sansano-Maestre, Jose, González, Fernando, Mateo Barrientos, Marta, Gómez-Muñoz, María Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458632/
https://www.ncbi.nlm.nih.gov/pubmed/37624008
http://dx.doi.org/10.3390/pathogens12081048
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author Azami-Conesa, Iris
Pérez-Moreno, Paula
Matas Méndez, Pablo
Sansano-Maestre, Jose
González, Fernando
Mateo Barrientos, Marta
Gómez-Muñoz, María Teresa
author_facet Azami-Conesa, Iris
Pérez-Moreno, Paula
Matas Méndez, Pablo
Sansano-Maestre, Jose
González, Fernando
Mateo Barrientos, Marta
Gómez-Muñoz, María Teresa
author_sort Azami-Conesa, Iris
collection PubMed
description Zoonotic leishmaniasis caused by Leishmania infantum is distributed worldwide and affects humans and domestic and wild mammals. In Europe, specifically in the Mediterranean basin, leishmaniasis is endemic due to the concurrence of the phlebotomine vectors and reservoir mammals, including carnivorous wildlife species and other less studied wild species. In this article, spleen, skin, and eye or oral swabs taken from 134 wild mammals admitted to five wildlife recovery centers in Spain were used. PCR employing fragments of the Repeat region, ITS1, and SSUrRNA were used for detection, and positive samples were processed for sequencing. L. infantum was detected in three out of the nine species analyzed, including European hedgehog, European badger, and red squirrel, with percentages ranging from 11.53 to 35.71%, depending on the species. Most of the species showed higher percentages of positivity in spleen samples than in skin samples. A small number of animals from the remaining six species tested negative, including Algerian hedgehog, stone marten, least weasel, garden dormouse, western polecat, and Egyptian mongoose. Hedgehogs and badgers are good candidates for consideration as epidemiological sentinels and pose a higher risk as potential reservoirs of leishmaniasis based on their percentage of infection and wide distribution.
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spelling pubmed-104586322023-08-27 Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain Azami-Conesa, Iris Pérez-Moreno, Paula Matas Méndez, Pablo Sansano-Maestre, Jose González, Fernando Mateo Barrientos, Marta Gómez-Muñoz, María Teresa Pathogens Article Zoonotic leishmaniasis caused by Leishmania infantum is distributed worldwide and affects humans and domestic and wild mammals. In Europe, specifically in the Mediterranean basin, leishmaniasis is endemic due to the concurrence of the phlebotomine vectors and reservoir mammals, including carnivorous wildlife species and other less studied wild species. In this article, spleen, skin, and eye or oral swabs taken from 134 wild mammals admitted to five wildlife recovery centers in Spain were used. PCR employing fragments of the Repeat region, ITS1, and SSUrRNA were used for detection, and positive samples were processed for sequencing. L. infantum was detected in three out of the nine species analyzed, including European hedgehog, European badger, and red squirrel, with percentages ranging from 11.53 to 35.71%, depending on the species. Most of the species showed higher percentages of positivity in spleen samples than in skin samples. A small number of animals from the remaining six species tested negative, including Algerian hedgehog, stone marten, least weasel, garden dormouse, western polecat, and Egyptian mongoose. Hedgehogs and badgers are good candidates for consideration as epidemiological sentinels and pose a higher risk as potential reservoirs of leishmaniasis based on their percentage of infection and wide distribution. MDPI 2023-08-16 /pmc/articles/PMC10458632/ /pubmed/37624008 http://dx.doi.org/10.3390/pathogens12081048 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Azami-Conesa, Iris
Pérez-Moreno, Paula
Matas Méndez, Pablo
Sansano-Maestre, Jose
González, Fernando
Mateo Barrientos, Marta
Gómez-Muñoz, María Teresa
Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain
title Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain
title_full Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain
title_fullStr Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain
title_full_unstemmed Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain
title_short Occurrence of Leishmania infantum in Wild Mammals Admitted to Recovery Centers in Spain
title_sort occurrence of leishmania infantum in wild mammals admitted to recovery centers in spain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458632/
https://www.ncbi.nlm.nih.gov/pubmed/37624008
http://dx.doi.org/10.3390/pathogens12081048
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