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Chemistry and Pharmacology of Fluorinated Drugs Approved by the FDA (2016–2022)
Fluorine is characterized by high electronegativity and small atomic size, which provide this molecule with the unique property of augmenting the potency, selectivity, metabolic stability, and pharmacokinetics of drugs. Fluorine (F) substitution has been extensively explored in drug research as a me...
Autores principales: | Shabir, Ghulam, Saeed, Aamer, Zahid, Wajeeha, Naseer, Fatima, Riaz, Zainab, Khalil, Nafeesa, Muneeba, Albericio, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458641/ https://www.ncbi.nlm.nih.gov/pubmed/37631077 http://dx.doi.org/10.3390/ph16081162 |
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