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Effect of Gut Microbiota on the Pharmacokinetics of Nifedipine in Spontaneously Hypertensive Rats

The pharmacokinetic variability of nifedipine widely observed in the clinic cannot be fully explained by pharmacogenomics. As a new factor affecting drug metabolism, how the gut microbiota affects the pharmacokinetics of nifedipine needs to be explored. Spontaneously hypertensive rats (SHRs) have be...

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Detalles Bibliográficos
Autores principales:	Zhou, Rong, Yang, Haijun, Zhu, Peng, Liu, Yujie, Zhang, Yanjuan, Zhang, Wei, Zhou, Honghao, Li, Xiong, Li, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458652/ https://www.ncbi.nlm.nih.gov/pubmed/37631299 http://dx.doi.org/10.3390/pharmaceutics15082085

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