The mitochondria-targeted sulfide delivery molecule attenuates drugs-induced gastropathy. Involvement of heme oxygenase pathway.

Hydrogen sulfide (H(2)S) signaling and H(2)S-prodrugs maintain redox balance in gastrointestinal (GI) tract. Predominant effect of any H(2)S-donor is mitochondrial. Non-targeted H(2)S-moieties were shown to decrease the non-steroidal anti-inflammatory drugs (NSAIDs)-induced gastrotoxicity but in hig...

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Detalles Bibliográficos
Autores principales: Magierowska, Katarzyna, Wójcik-Grzybek, Dagmara, Korbut, Edyta, Bakalarz, Dominik, Ginter, Grzegorz, Danielak, Aleksandra, Kwiecień, Sławomir, Chmura, Anna, Torregrossa, Roberta, Whiteman, Matthew, Magierowski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458696/
https://www.ncbi.nlm.nih.gov/pubmed/37597422
http://dx.doi.org/10.1016/j.redox.2023.102847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458696/
https://www.ncbi.nlm.nih.gov/pubmed/37597422
http://dx.doi.org/10.1016/j.redox.2023.102847

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