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Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review

Control and treatment programs (CDTI) have been set up nationally in all endemic countries to overcome the impact of onchocerciasis on the affected populations. However, Gabon must still succeed in setting up real onchocerciasis control programs. Here, various database articles have been used to pro...

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Autores principales: Eyang-Assengone, Elsa-Rush, Makouloutou-Nzassi, Patrice, Mbou-Boutambe, Clark, Bangueboussa, Félicien, Atsame, Julienne, Boundenga, Larson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458829/
https://www.ncbi.nlm.nih.gov/pubmed/37630506
http://dx.doi.org/10.3390/microorganisms11081946
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author Eyang-Assengone, Elsa-Rush
Makouloutou-Nzassi, Patrice
Mbou-Boutambe, Clark
Bangueboussa, Félicien
Atsame, Julienne
Boundenga, Larson
author_facet Eyang-Assengone, Elsa-Rush
Makouloutou-Nzassi, Patrice
Mbou-Boutambe, Clark
Bangueboussa, Félicien
Atsame, Julienne
Boundenga, Larson
author_sort Eyang-Assengone, Elsa-Rush
collection PubMed
description Control and treatment programs (CDTI) have been set up nationally in all endemic countries to overcome the impact of onchocerciasis on the affected populations. However, Gabon must still succeed in setting up real onchocerciasis control programs. Here, various database articles have been used to provide the scientific community with a summary document showing the mapping of this disease in Gabon. The articles dealing with onchocerciasis, animal reservoirs, surveillance, and elimination were analyzed. Results showed that little research has been performed. Most studies are concentrated in one region (The area of Lastourville). In addition, we observed that the distribution of the disease varies significantly across the country. Indeed, specific environments present a hyper-endemicity of the disease, while others are meso and hypo-endemic. So, we found some departments with a prevalence ranging from 0% to over 20%; within them, villages had infection levels comprising 10% to 60%, indicating potential hotspots. Vectors activities were studied in some areas. This paper showed the challenges encountered in the country to eliminate this disease. One solution is a deeper understanding of the disease’s bioecology to establish effective health policies to eliminate onchocerciasis in Gabon effectively.
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spelling pubmed-104588292023-08-27 Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review Eyang-Assengone, Elsa-Rush Makouloutou-Nzassi, Patrice Mbou-Boutambe, Clark Bangueboussa, Félicien Atsame, Julienne Boundenga, Larson Microorganisms Review Control and treatment programs (CDTI) have been set up nationally in all endemic countries to overcome the impact of onchocerciasis on the affected populations. However, Gabon must still succeed in setting up real onchocerciasis control programs. Here, various database articles have been used to provide the scientific community with a summary document showing the mapping of this disease in Gabon. The articles dealing with onchocerciasis, animal reservoirs, surveillance, and elimination were analyzed. Results showed that little research has been performed. Most studies are concentrated in one region (The area of Lastourville). In addition, we observed that the distribution of the disease varies significantly across the country. Indeed, specific environments present a hyper-endemicity of the disease, while others are meso and hypo-endemic. So, we found some departments with a prevalence ranging from 0% to over 20%; within them, villages had infection levels comprising 10% to 60%, indicating potential hotspots. Vectors activities were studied in some areas. This paper showed the challenges encountered in the country to eliminate this disease. One solution is a deeper understanding of the disease’s bioecology to establish effective health policies to eliminate onchocerciasis in Gabon effectively. MDPI 2023-07-29 /pmc/articles/PMC10458829/ /pubmed/37630506 http://dx.doi.org/10.3390/microorganisms11081946 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Eyang-Assengone, Elsa-Rush
Makouloutou-Nzassi, Patrice
Mbou-Boutambe, Clark
Bangueboussa, Félicien
Atsame, Julienne
Boundenga, Larson
Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review
title Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review
title_full Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review
title_fullStr Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review
title_full_unstemmed Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review
title_short Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review
title_sort status of onchocerciasis elimination in gabon and challenges: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458829/
https://www.ncbi.nlm.nih.gov/pubmed/37630506
http://dx.doi.org/10.3390/microorganisms11081946
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