Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)

In this report, we describe a case of a 5-year-old girl with poor growth and unresolving pneumonia. Bronchoscopy showed numerous endobronchial mucosal nodules, consisting of dense lymphoid infiltrates. Bacterial culture of the nodule biopsy suggested endobronchial actinomycosis. Genetic test confirm...

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Detalles Bibliográficos
Autores principales: Lam, Kwan Fung, Chan, Shun, Kam, Lok Sang, Kwok, Janette, Lee, Pamela Pui-Wah, Lam, David Shu Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458975/
https://www.ncbi.nlm.nih.gov/pubmed/37635731
http://dx.doi.org/10.1016/j.rmcr.2023.101909
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author Lam, Kwan Fung
Chan, Shun
Kam, Lok Sang
Kwok, Janette
Lee, Pamela Pui-Wah
Lam, David Shu Yan
author_facet Lam, Kwan Fung
Chan, Shun
Kam, Lok Sang
Kwok, Janette
Lee, Pamela Pui-Wah
Lam, David Shu Yan
author_sort Lam, Kwan Fung
collection PubMed
description In this report, we describe a case of a 5-year-old girl with poor growth and unresolving pneumonia. Bronchoscopy showed numerous endobronchial mucosal nodules, consisting of dense lymphoid infiltrates. Bacterial culture of the nodule biopsy suggested endobronchial actinomycosis. Genetic test confirmed the diagnosis of APDS.
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spelling pubmed-104589752023-08-27 Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS) Lam, Kwan Fung Chan, Shun Kam, Lok Sang Kwok, Janette Lee, Pamela Pui-Wah Lam, David Shu Yan Respir Med Case Rep Case Report In this report, we describe a case of a 5-year-old girl with poor growth and unresolving pneumonia. Bronchoscopy showed numerous endobronchial mucosal nodules, consisting of dense lymphoid infiltrates. Bacterial culture of the nodule biopsy suggested endobronchial actinomycosis. Genetic test confirmed the diagnosis of APDS. Elsevier 2023-08-15 /pmc/articles/PMC10458975/ /pubmed/37635731 http://dx.doi.org/10.1016/j.rmcr.2023.101909 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Lam, Kwan Fung
Chan, Shun
Kam, Lok Sang
Kwok, Janette
Lee, Pamela Pui-Wah
Lam, David Shu Yan
Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)
title Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)
title_full Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)
title_fullStr Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)
title_full_unstemmed Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)
title_short Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)
title_sort endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (apds)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458975/
https://www.ncbi.nlm.nih.gov/pubmed/37635731
http://dx.doi.org/10.1016/j.rmcr.2023.101909
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