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Blocking the CGRP Receptor: Differences across Human Vascular Beds

Multiple drugs targeting the calcitonin gene-related peptide (CGRP) receptor have been developed for the treatment of migraine. Here, the effect of the small-molecule CGRP receptor antagonist zavegepant (0.1 nM–1 µM) on CGRP-induced relaxation in isolated human coronary arteries (HCAs) was investiga...

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Detalles Bibliográficos
Autores principales: de Vries, Tessa, Boucherie, Deirdre M., van den Bogaerdt, Antoon, Danser, A. H. Jan, MaassenVanDenBrink, Antoinette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459004/
https://www.ncbi.nlm.nih.gov/pubmed/37630989
http://dx.doi.org/10.3390/ph16081075