Cargando…

The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation

The aim of the study was to investigate the effects of seasonal variability of insolation, the implementation of new recommendations for vitamin D supplementation (2018), and the SARS-CoV-2 pandemic lockdown (2020) on 25(OH)D concentrations in children from central Poland. The retrospective analysis...

Descripción completa

Detalles Bibliográficos
Autores principales: Smyczyńska, Joanna, Pawelak, Natalia, Hilczer, Maciej, Łupińska, Anna, Lewiński, Andrzej, Stawerska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459029/
https://www.ncbi.nlm.nih.gov/pubmed/37630820
http://dx.doi.org/10.3390/nu15163629
_version_ 1785097309548183552
author Smyczyńska, Joanna
Pawelak, Natalia
Hilczer, Maciej
Łupińska, Anna
Lewiński, Andrzej
Stawerska, Renata
author_facet Smyczyńska, Joanna
Pawelak, Natalia
Hilczer, Maciej
Łupińska, Anna
Lewiński, Andrzej
Stawerska, Renata
author_sort Smyczyńska, Joanna
collection PubMed
description The aim of the study was to investigate the effects of seasonal variability of insolation, the implementation of new recommendations for vitamin D supplementation (2018), and the SARS-CoV-2 pandemic lockdown (2020) on 25(OH)D concentrations in children from central Poland. The retrospective analysis of variability of 25(OH)D concentrations during the last 8 years was performed in a group of 1440 children with short stature, aged 3.0–18.0 years. Significant differences in 25(OH)D concentrations were found between the periods from mid-2014 to mid-2018, from mid-2018 to mid-2020, and from mid-2020 to mid-2022 (medians: 22.9, 26.0, and 29.9 ng/mL, respectively). Time series models created on the grounds of data from 6 years of the pre-pandemic period and used for prediction for the pandemic period explained over 80% of the seasonal variability of 25(OH)D concentrations, with overprediction for the first year of the pandemic and underprediction for the second year. A significant increase in 25(OH)D concentrations was observed both after the introduction of new vitamin D supplementation guidelines and during the SARS-CoV-2 pandemic; however, the scale of vitamin D deficiency and insufficiency was still too high. Time series models are useful in analyzing the impact of health policy interventions and pandemic restrictions on the seasonal variability of vitamin D concentrations.
format Online
Article
Text
id pubmed-10459029
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104590292023-08-27 The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation Smyczyńska, Joanna Pawelak, Natalia Hilczer, Maciej Łupińska, Anna Lewiński, Andrzej Stawerska, Renata Nutrients Article The aim of the study was to investigate the effects of seasonal variability of insolation, the implementation of new recommendations for vitamin D supplementation (2018), and the SARS-CoV-2 pandemic lockdown (2020) on 25(OH)D concentrations in children from central Poland. The retrospective analysis of variability of 25(OH)D concentrations during the last 8 years was performed in a group of 1440 children with short stature, aged 3.0–18.0 years. Significant differences in 25(OH)D concentrations were found between the periods from mid-2014 to mid-2018, from mid-2018 to mid-2020, and from mid-2020 to mid-2022 (medians: 22.9, 26.0, and 29.9 ng/mL, respectively). Time series models created on the grounds of data from 6 years of the pre-pandemic period and used for prediction for the pandemic period explained over 80% of the seasonal variability of 25(OH)D concentrations, with overprediction for the first year of the pandemic and underprediction for the second year. A significant increase in 25(OH)D concentrations was observed both after the introduction of new vitamin D supplementation guidelines and during the SARS-CoV-2 pandemic; however, the scale of vitamin D deficiency and insufficiency was still too high. Time series models are useful in analyzing the impact of health policy interventions and pandemic restrictions on the seasonal variability of vitamin D concentrations. MDPI 2023-08-18 /pmc/articles/PMC10459029/ /pubmed/37630820 http://dx.doi.org/10.3390/nu15163629 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Smyczyńska, Joanna
Pawelak, Natalia
Hilczer, Maciej
Łupińska, Anna
Lewiński, Andrzej
Stawerska, Renata
The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation
title The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation
title_full The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation
title_fullStr The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation
title_full_unstemmed The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation
title_short The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation
title_sort variability of vitamin d concentrations in short children with short stature from central poland—the effects of insolation, supplementation, and covid-19 pandemic isolation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459029/
https://www.ncbi.nlm.nih.gov/pubmed/37630820
http://dx.doi.org/10.3390/nu15163629
work_keys_str_mv AT smyczynskajoanna thevariabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT pawelaknatalia thevariabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT hilczermaciej thevariabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT łupinskaanna thevariabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT lewinskiandrzej thevariabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT stawerskarenata thevariabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT smyczynskajoanna variabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT pawelaknatalia variabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT hilczermaciej variabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT łupinskaanna variabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT lewinskiandrzej variabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation
AT stawerskarenata variabilityofvitamindconcentrationsinshortchildrenwithshortstaturefromcentralpolandtheeffectsofinsolationsupplementationandcovid19pandemicisolation