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The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation
The aim of the study was to investigate the effects of seasonal variability of insolation, the implementation of new recommendations for vitamin D supplementation (2018), and the SARS-CoV-2 pandemic lockdown (2020) on 25(OH)D concentrations in children from central Poland. The retrospective analysis...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459029/ https://www.ncbi.nlm.nih.gov/pubmed/37630820 http://dx.doi.org/10.3390/nu15163629 |
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author | Smyczyńska, Joanna Pawelak, Natalia Hilczer, Maciej Łupińska, Anna Lewiński, Andrzej Stawerska, Renata |
author_facet | Smyczyńska, Joanna Pawelak, Natalia Hilczer, Maciej Łupińska, Anna Lewiński, Andrzej Stawerska, Renata |
author_sort | Smyczyńska, Joanna |
collection | PubMed |
description | The aim of the study was to investigate the effects of seasonal variability of insolation, the implementation of new recommendations for vitamin D supplementation (2018), and the SARS-CoV-2 pandemic lockdown (2020) on 25(OH)D concentrations in children from central Poland. The retrospective analysis of variability of 25(OH)D concentrations during the last 8 years was performed in a group of 1440 children with short stature, aged 3.0–18.0 years. Significant differences in 25(OH)D concentrations were found between the periods from mid-2014 to mid-2018, from mid-2018 to mid-2020, and from mid-2020 to mid-2022 (medians: 22.9, 26.0, and 29.9 ng/mL, respectively). Time series models created on the grounds of data from 6 years of the pre-pandemic period and used for prediction for the pandemic period explained over 80% of the seasonal variability of 25(OH)D concentrations, with overprediction for the first year of the pandemic and underprediction for the second year. A significant increase in 25(OH)D concentrations was observed both after the introduction of new vitamin D supplementation guidelines and during the SARS-CoV-2 pandemic; however, the scale of vitamin D deficiency and insufficiency was still too high. Time series models are useful in analyzing the impact of health policy interventions and pandemic restrictions on the seasonal variability of vitamin D concentrations. |
format | Online Article Text |
id | pubmed-10459029 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104590292023-08-27 The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation Smyczyńska, Joanna Pawelak, Natalia Hilczer, Maciej Łupińska, Anna Lewiński, Andrzej Stawerska, Renata Nutrients Article The aim of the study was to investigate the effects of seasonal variability of insolation, the implementation of new recommendations for vitamin D supplementation (2018), and the SARS-CoV-2 pandemic lockdown (2020) on 25(OH)D concentrations in children from central Poland. The retrospective analysis of variability of 25(OH)D concentrations during the last 8 years was performed in a group of 1440 children with short stature, aged 3.0–18.0 years. Significant differences in 25(OH)D concentrations were found between the periods from mid-2014 to mid-2018, from mid-2018 to mid-2020, and from mid-2020 to mid-2022 (medians: 22.9, 26.0, and 29.9 ng/mL, respectively). Time series models created on the grounds of data from 6 years of the pre-pandemic period and used for prediction for the pandemic period explained over 80% of the seasonal variability of 25(OH)D concentrations, with overprediction for the first year of the pandemic and underprediction for the second year. A significant increase in 25(OH)D concentrations was observed both after the introduction of new vitamin D supplementation guidelines and during the SARS-CoV-2 pandemic; however, the scale of vitamin D deficiency and insufficiency was still too high. Time series models are useful in analyzing the impact of health policy interventions and pandemic restrictions on the seasonal variability of vitamin D concentrations. MDPI 2023-08-18 /pmc/articles/PMC10459029/ /pubmed/37630820 http://dx.doi.org/10.3390/nu15163629 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Smyczyńska, Joanna Pawelak, Natalia Hilczer, Maciej Łupińska, Anna Lewiński, Andrzej Stawerska, Renata The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation |
title | The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation |
title_full | The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation |
title_fullStr | The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation |
title_full_unstemmed | The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation |
title_short | The Variability of Vitamin D Concentrations in Short Children with Short Stature from Central Poland—The Effects of Insolation, Supplementation, and COVID-19 Pandemic Isolation |
title_sort | variability of vitamin d concentrations in short children with short stature from central poland—the effects of insolation, supplementation, and covid-19 pandemic isolation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459029/ https://www.ncbi.nlm.nih.gov/pubmed/37630820 http://dx.doi.org/10.3390/nu15163629 |
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