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Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice

SIMPLE SUMMARY: The results of this test suggest that serum amyloid A is a sensitive and reliable index of inflammation without disease specificity in Japanese Black cattle. Moreover, the serum amyloid A concentration can evaluate the prognosis and therapeutic effects in diseased cattle more objecti...

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Autores principales: Shinya, Urara, Yamato, Osamu, Iwamura, Yuka, Kato, Tomohiro, Hamada, Yuhei, Widodo, Oky Setyo, Taniguchi, Masayasu, Takagi, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459075/
https://www.ncbi.nlm.nih.gov/pubmed/37624315
http://dx.doi.org/10.3390/vetsci10080528
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author Shinya, Urara
Yamato, Osamu
Iwamura, Yuka
Kato, Tomohiro
Hamada, Yuhei
Widodo, Oky Setyo
Taniguchi, Masayasu
Takagi, Mitsuhiro
author_facet Shinya, Urara
Yamato, Osamu
Iwamura, Yuka
Kato, Tomohiro
Hamada, Yuhei
Widodo, Oky Setyo
Taniguchi, Masayasu
Takagi, Mitsuhiro
author_sort Shinya, Urara
collection PubMed
description SIMPLE SUMMARY: The results of this test suggest that serum amyloid A is a sensitive and reliable index of inflammation without disease specificity in Japanese Black cattle. Moreover, the serum amyloid A concentration can evaluate the prognosis and therapeutic effects in diseased cattle more objectively. ABSTRACT: This study investigated the concentration of serum amyloid A (SAA), an acute phase protein, in Japanese Black cattle. Four practical trials were performed to evaluate the transition of SAA and sialic acid before and after dehorning, the relationship between the SAA concentration and other blood test parameters, the SAA dynamics in the diseased cattle, and the blood test results, including the SAA concentrations, of the two cases with a follow-up. The SAA concentration increased with dehorning but decreased 7 days after dehorning. The SAA concentration is positively correlated with the α-globulin, sialic acid, and fibrinogen concentrations and negatively correlated with the serum iron concentration. The SAA concentration in the deceased herd was significantly higher than that in the cured outcome herd. In addition, the SAA concentration in the cured group decreased significantly from the first test to retesting but increased significantly in the disuse group. Thus, SAA is a sensitive index of inflammation and a monitoring tool in Japanese Black cattle, and its measurement is considered useful in clinical practice.
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spelling pubmed-104590752023-08-27 Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice Shinya, Urara Yamato, Osamu Iwamura, Yuka Kato, Tomohiro Hamada, Yuhei Widodo, Oky Setyo Taniguchi, Masayasu Takagi, Mitsuhiro Vet Sci Communication SIMPLE SUMMARY: The results of this test suggest that serum amyloid A is a sensitive and reliable index of inflammation without disease specificity in Japanese Black cattle. Moreover, the serum amyloid A concentration can evaluate the prognosis and therapeutic effects in diseased cattle more objectively. ABSTRACT: This study investigated the concentration of serum amyloid A (SAA), an acute phase protein, in Japanese Black cattle. Four practical trials were performed to evaluate the transition of SAA and sialic acid before and after dehorning, the relationship between the SAA concentration and other blood test parameters, the SAA dynamics in the diseased cattle, and the blood test results, including the SAA concentrations, of the two cases with a follow-up. The SAA concentration increased with dehorning but decreased 7 days after dehorning. The SAA concentration is positively correlated with the α-globulin, sialic acid, and fibrinogen concentrations and negatively correlated with the serum iron concentration. The SAA concentration in the deceased herd was significantly higher than that in the cured outcome herd. In addition, the SAA concentration in the cured group decreased significantly from the first test to retesting but increased significantly in the disuse group. Thus, SAA is a sensitive index of inflammation and a monitoring tool in Japanese Black cattle, and its measurement is considered useful in clinical practice. MDPI 2023-08-17 /pmc/articles/PMC10459075/ /pubmed/37624315 http://dx.doi.org/10.3390/vetsci10080528 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Shinya, Urara
Yamato, Osamu
Iwamura, Yuka
Kato, Tomohiro
Hamada, Yuhei
Widodo, Oky Setyo
Taniguchi, Masayasu
Takagi, Mitsuhiro
Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice
title Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice
title_full Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice
title_fullStr Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice
title_full_unstemmed Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice
title_short Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice
title_sort usefulness of measuring serum amyloid a concentration in japanese black cattle in clinical practice
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459075/
https://www.ncbi.nlm.nih.gov/pubmed/37624315
http://dx.doi.org/10.3390/vetsci10080528
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