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Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo

(1) Introduction: The Democratic Republic of the Congo (DRC) has one of the largest cohorts of un- and under-vaccinated children worldwide. This study aimed to identify and compare the main reasons for there being zero-dose (ZD) or under-vaccinated children in the DRC. (2) Methods: This is a seconda...

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Autores principales: Ishoso, Daniel Katuashi, Mafuta, Eric, Danovaro-Holliday, M. Carolina, Ngandu, Christian, Menning, Lisa, Cikomola, Aimé Mwana-Wabene, Lungayo, Christophe Luhata, Mukendi, Jean-Crispin, Mwamba, Dieudonné, Mboussou, Franck-Fortune, Manirakiza, Deo, Yapi, Moise Désiré, Ngabo, Gaga Fidele, Riziki, Richard Bahizire, Aluma, Adele Daleke Lisi, Tsobeng, Bienvenu Nguejio, Mwanga, Cedric, Otomba, John, Lulebo, Aimée, Lusamba, Paul, Nimpa, Marcellin Mengouo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459103/
https://www.ncbi.nlm.nih.gov/pubmed/37631938
http://dx.doi.org/10.3390/vaccines11081370
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author Ishoso, Daniel Katuashi
Mafuta, Eric
Danovaro-Holliday, M. Carolina
Ngandu, Christian
Menning, Lisa
Cikomola, Aimé Mwana-Wabene
Lungayo, Christophe Luhata
Mukendi, Jean-Crispin
Mwamba, Dieudonné
Mboussou, Franck-Fortune
Manirakiza, Deo
Yapi, Moise Désiré
Ngabo, Gaga Fidele
Riziki, Richard Bahizire
Aluma, Adele Daleke Lisi
Tsobeng, Bienvenu Nguejio
Mwanga, Cedric
Otomba, John
Lulebo, Aimée
Lusamba, Paul
Nimpa, Marcellin Mengouo
author_facet Ishoso, Daniel Katuashi
Mafuta, Eric
Danovaro-Holliday, M. Carolina
Ngandu, Christian
Menning, Lisa
Cikomola, Aimé Mwana-Wabene
Lungayo, Christophe Luhata
Mukendi, Jean-Crispin
Mwamba, Dieudonné
Mboussou, Franck-Fortune
Manirakiza, Deo
Yapi, Moise Désiré
Ngabo, Gaga Fidele
Riziki, Richard Bahizire
Aluma, Adele Daleke Lisi
Tsobeng, Bienvenu Nguejio
Mwanga, Cedric
Otomba, John
Lulebo, Aimée
Lusamba, Paul
Nimpa, Marcellin Mengouo
author_sort Ishoso, Daniel Katuashi
collection PubMed
description (1) Introduction: The Democratic Republic of the Congo (DRC) has one of the largest cohorts of un- and under-vaccinated children worldwide. This study aimed to identify and compare the main reasons for there being zero-dose (ZD) or under-vaccinated children in the DRC. (2) Methods: This is a secondary analysis derived from a province-level vaccination coverage survey conducted between November 2021 and February 2022; this survey included questions about the reasons for not receiving one or more vaccines. A zero-dose child (ZD) was a person aged 12–23 months not having received any pentavalent vaccine (diphtheria–tetanus–pertussis–Hemophilus influenzae type b (Hib)–Hepatitis B) as per card or caregiver recall and an under-vaccinated child was one who had not received the third dose of the pentavalent vaccine. The proportions of the reasons for non-vaccination were first presented using the WHO-endorsed behavioral and social drivers for vaccination (BeSD) conceptual framework and then compared across the groups of ZD and under-vaccinated children using the Rao–Scott chi-square test; analyses were conducted at province and national level, and accounting for the sample approach. (3) Results: Of the 51,054 children aged 12–23 m in the survey sample, 19,676 ZD and under-vaccinated children were included in the study. For the ZD children, reasons related to people’s thinking and feelings were cited as 64.03% and those related to social reasons as 31.13%; both proportions were higher than for under-vaccinated children (44.7% and 26.2%, respectively, p < 0.001). Regarding intentions to vaccinate their children, 82.15% of the parents/guardians of the ZD children said they wanted their children to receive “none” of the recommended vaccines, which was significantly higher than for the under-vaccinated children. In contrast, “practical issues” were cited for 35.60% of the ZD children, compared to 55.60% for the under-vaccinated children (p < 0.001). The distribution of reasons varied between provinces, e.g., 12 of the 26 provinces had a proportion of reasons for the ZD children relating to practical issues that was higher than the national level. (4) Conclusions: reasons provided for non-vaccination among the ZD children in the DRC were largely related to lack of parental/guardian motivation to have their children vaccinated, while reasons among under-vaccinated children were mostly related to practical issues. These results can help inform decision-makers to direct vaccination interventions.
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spelling pubmed-104591032023-08-27 Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo Ishoso, Daniel Katuashi Mafuta, Eric Danovaro-Holliday, M. Carolina Ngandu, Christian Menning, Lisa Cikomola, Aimé Mwana-Wabene Lungayo, Christophe Luhata Mukendi, Jean-Crispin Mwamba, Dieudonné Mboussou, Franck-Fortune Manirakiza, Deo Yapi, Moise Désiré Ngabo, Gaga Fidele Riziki, Richard Bahizire Aluma, Adele Daleke Lisi Tsobeng, Bienvenu Nguejio Mwanga, Cedric Otomba, John Lulebo, Aimée Lusamba, Paul Nimpa, Marcellin Mengouo Vaccines (Basel) Article (1) Introduction: The Democratic Republic of the Congo (DRC) has one of the largest cohorts of un- and under-vaccinated children worldwide. This study aimed to identify and compare the main reasons for there being zero-dose (ZD) or under-vaccinated children in the DRC. (2) Methods: This is a secondary analysis derived from a province-level vaccination coverage survey conducted between November 2021 and February 2022; this survey included questions about the reasons for not receiving one or more vaccines. A zero-dose child (ZD) was a person aged 12–23 months not having received any pentavalent vaccine (diphtheria–tetanus–pertussis–Hemophilus influenzae type b (Hib)–Hepatitis B) as per card or caregiver recall and an under-vaccinated child was one who had not received the third dose of the pentavalent vaccine. The proportions of the reasons for non-vaccination were first presented using the WHO-endorsed behavioral and social drivers for vaccination (BeSD) conceptual framework and then compared across the groups of ZD and under-vaccinated children using the Rao–Scott chi-square test; analyses were conducted at province and national level, and accounting for the sample approach. (3) Results: Of the 51,054 children aged 12–23 m in the survey sample, 19,676 ZD and under-vaccinated children were included in the study. For the ZD children, reasons related to people’s thinking and feelings were cited as 64.03% and those related to social reasons as 31.13%; both proportions were higher than for under-vaccinated children (44.7% and 26.2%, respectively, p < 0.001). Regarding intentions to vaccinate their children, 82.15% of the parents/guardians of the ZD children said they wanted their children to receive “none” of the recommended vaccines, which was significantly higher than for the under-vaccinated children. In contrast, “practical issues” were cited for 35.60% of the ZD children, compared to 55.60% for the under-vaccinated children (p < 0.001). The distribution of reasons varied between provinces, e.g., 12 of the 26 provinces had a proportion of reasons for the ZD children relating to practical issues that was higher than the national level. (4) Conclusions: reasons provided for non-vaccination among the ZD children in the DRC were largely related to lack of parental/guardian motivation to have their children vaccinated, while reasons among under-vaccinated children were mostly related to practical issues. These results can help inform decision-makers to direct vaccination interventions. MDPI 2023-08-16 /pmc/articles/PMC10459103/ /pubmed/37631938 http://dx.doi.org/10.3390/vaccines11081370 Text en © World Health Organization 2023. https://creativecommons.org/licenses/by/3.0/igo/Licensee MDPI. This article is distributed under the terms of the Creative Commons Attribution IGO License. (https://creativecommons.org/licenses/by/3.0/igo/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted.
spellingShingle Article
Ishoso, Daniel Katuashi
Mafuta, Eric
Danovaro-Holliday, M. Carolina
Ngandu, Christian
Menning, Lisa
Cikomola, Aimé Mwana-Wabene
Lungayo, Christophe Luhata
Mukendi, Jean-Crispin
Mwamba, Dieudonné
Mboussou, Franck-Fortune
Manirakiza, Deo
Yapi, Moise Désiré
Ngabo, Gaga Fidele
Riziki, Richard Bahizire
Aluma, Adele Daleke Lisi
Tsobeng, Bienvenu Nguejio
Mwanga, Cedric
Otomba, John
Lulebo, Aimée
Lusamba, Paul
Nimpa, Marcellin Mengouo
Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo
title Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo
title_full Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo
title_fullStr Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo
title_full_unstemmed Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo
title_short Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo
title_sort reasons for being “zero-dose and under-vaccinated” among children aged 12–23 months in the democratic republic of the congo
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459103/
https://www.ncbi.nlm.nih.gov/pubmed/37631938
http://dx.doi.org/10.3390/vaccines11081370
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