Cargando…

The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation

Haematopoietic stem cell transplantation (HSCT) is a treatment option for many haematological conditions in patients of all ages. Nutritional support is important at each stage of treatment, but particular nutritional needs and dictated support occur during the preparatory (conditioning regimen) and...

Descripción completa

Detalles Bibliográficos
Autores principales: Pawłowski, Piotr, Pawłowska, Paulina, Ziętara, Karolina Joanna, Samardakiewicz, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459351/
https://www.ncbi.nlm.nih.gov/pubmed/37630748
http://dx.doi.org/10.3390/nu15163558
_version_ 1785097390484619264
author Pawłowski, Piotr
Pawłowska, Paulina
Ziętara, Karolina Joanna
Samardakiewicz, Marzena
author_facet Pawłowski, Piotr
Pawłowska, Paulina
Ziętara, Karolina Joanna
Samardakiewicz, Marzena
author_sort Pawłowski, Piotr
collection PubMed
description Haematopoietic stem cell transplantation (HSCT) is a treatment option for many haematological conditions in patients of all ages. Nutritional support is important at each stage of treatment, but particular nutritional needs and dictated support occur during the preparatory (conditioning regimen) and post-transplant periods. Patients may require nutritional treatment by the enteral or parenteral route. The quantitative and qualitative composition of meals may change. Vitamin requirements, including vitamin D and vitamin C, might also be different. An adequately composed diet, adapted to the needs of the patient, may influence the occurrence of complications such as graft-versus-host disease (GvHD), gastrointestinal disorders, infections, and reduced survival time. Haematological diseases as well as transplantation can negatively affect the intestinal flora, with negative consequences in the form of mucosal inflammation and disorders of a functional nature. Currently, aspects related to nutrition are crucial in the care of patients after HSCT, and numerous studies, including randomized trials on these aspects, are being conducted. This study serves the critical analysis of current scientific evidence regarding nutritional support for patients after HSCT.
format Online
Article
Text
id pubmed-10459351
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104593512023-08-27 The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation Pawłowski, Piotr Pawłowska, Paulina Ziętara, Karolina Joanna Samardakiewicz, Marzena Nutrients Review Haematopoietic stem cell transplantation (HSCT) is a treatment option for many haematological conditions in patients of all ages. Nutritional support is important at each stage of treatment, but particular nutritional needs and dictated support occur during the preparatory (conditioning regimen) and post-transplant periods. Patients may require nutritional treatment by the enteral or parenteral route. The quantitative and qualitative composition of meals may change. Vitamin requirements, including vitamin D and vitamin C, might also be different. An adequately composed diet, adapted to the needs of the patient, may influence the occurrence of complications such as graft-versus-host disease (GvHD), gastrointestinal disorders, infections, and reduced survival time. Haematological diseases as well as transplantation can negatively affect the intestinal flora, with negative consequences in the form of mucosal inflammation and disorders of a functional nature. Currently, aspects related to nutrition are crucial in the care of patients after HSCT, and numerous studies, including randomized trials on these aspects, are being conducted. This study serves the critical analysis of current scientific evidence regarding nutritional support for patients after HSCT. MDPI 2023-08-11 /pmc/articles/PMC10459351/ /pubmed/37630748 http://dx.doi.org/10.3390/nu15163558 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pawłowski, Piotr
Pawłowska, Paulina
Ziętara, Karolina Joanna
Samardakiewicz, Marzena
The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation
title The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation
title_full The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation
title_fullStr The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation
title_full_unstemmed The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation
title_short The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation
title_sort critical exploration into current evidence behind the role of the nutritional support in adult patients who undergo haematogenic stem cell transplantation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459351/
https://www.ncbi.nlm.nih.gov/pubmed/37630748
http://dx.doi.org/10.3390/nu15163558
work_keys_str_mv AT pawłowskipiotr thecriticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation
AT pawłowskapaulina thecriticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation
AT zietarakarolinajoanna thecriticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation
AT samardakiewiczmarzena thecriticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation
AT pawłowskipiotr criticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation
AT pawłowskapaulina criticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation
AT zietarakarolinajoanna criticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation
AT samardakiewiczmarzena criticalexplorationintocurrentevidencebehindtheroleofthenutritionalsupportinadultpatientswhoundergohaematogenicstemcelltransplantation