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Pregabalin–Tolperisone Combination to Treat Neuropathic Pain: Improved Analgesia and Reduced Side Effects in Rats
The current treatment of neuropathic pain (NP) is unsatisfactory; therefore, effective novel agents or combination-based analgesic therapies are needed. Herein, oral tolperisone, pregabalin, and duloxetine were tested for their antinociceptive effect against rat partial sciatic nerve ligation (pSNL)...
Autores principales: | Essmat, Nariman, Galambos, Anna Rita, Lakatos, Péter P., Karádi, Dávid Árpád, Mohammadzadeh, Amir, Abbood, Sarah Kadhim, Geda, Orsolya, Laufer, Rudolf, Király, Kornél, Riba, Pál, Zádori, Zoltán S., Szökő, Éva, Tábi, Tamás, Al-Khrasani, Mahmoud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459435/ https://www.ncbi.nlm.nih.gov/pubmed/37631030 http://dx.doi.org/10.3390/ph16081115 |
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