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Epilepsy Due to Solitary Calcified Cysticercus Granuloma

The calcified stage of the neurocysticercosis (NCC) is the common cause of acquired epilepsy in low and middle income countries in people aged > 20 years. Approximately 30% of adult onset seizures and epilepsy are attributable to NCC. In India and some of the Latin American countries, epilepsy du...

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Autor principal: Murthy, Jagarlapudi M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459524/
https://www.ncbi.nlm.nih.gov/pubmed/37623997
http://dx.doi.org/10.3390/pathogens12081037
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author Murthy, Jagarlapudi M. K.
author_facet Murthy, Jagarlapudi M. K.
author_sort Murthy, Jagarlapudi M. K.
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description The calcified stage of the neurocysticercosis (NCC) is the common cause of acquired epilepsy in low and middle income countries in people aged > 20 years. Approximately 30% of adult onset seizures and epilepsy are attributable to NCC. In India and some of the Latin American countries, epilepsy due to solitary calcified NCC is the common adult onset epilepsy. The current evidence suggests that the calcified cysticercus granuloma is probably the epileptogenic focus. The mechanisms involved in the epileptogenic process are not well understood; Focal-onset seizures with or without impaired awareness are the common seizure type. Focal-onset seizure can evolve to bilateral tonic-clonic seizure. Seizure outcome with anti-seizure medication, most often with monotherapy, is very good. The seizure disorders associated with various stages of NCC can be preventable.
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spelling pubmed-104595242023-08-27 Epilepsy Due to Solitary Calcified Cysticercus Granuloma Murthy, Jagarlapudi M. K. Pathogens Perspective The calcified stage of the neurocysticercosis (NCC) is the common cause of acquired epilepsy in low and middle income countries in people aged > 20 years. Approximately 30% of adult onset seizures and epilepsy are attributable to NCC. In India and some of the Latin American countries, epilepsy due to solitary calcified NCC is the common adult onset epilepsy. The current evidence suggests that the calcified cysticercus granuloma is probably the epileptogenic focus. The mechanisms involved in the epileptogenic process are not well understood; Focal-onset seizures with or without impaired awareness are the common seizure type. Focal-onset seizure can evolve to bilateral tonic-clonic seizure. Seizure outcome with anti-seizure medication, most often with monotherapy, is very good. The seizure disorders associated with various stages of NCC can be preventable. MDPI 2023-08-14 /pmc/articles/PMC10459524/ /pubmed/37623997 http://dx.doi.org/10.3390/pathogens12081037 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Murthy, Jagarlapudi M. K.
Epilepsy Due to Solitary Calcified Cysticercus Granuloma
title Epilepsy Due to Solitary Calcified Cysticercus Granuloma
title_full Epilepsy Due to Solitary Calcified Cysticercus Granuloma
title_fullStr Epilepsy Due to Solitary Calcified Cysticercus Granuloma
title_full_unstemmed Epilepsy Due to Solitary Calcified Cysticercus Granuloma
title_short Epilepsy Due to Solitary Calcified Cysticercus Granuloma
title_sort epilepsy due to solitary calcified cysticercus granuloma
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459524/
https://www.ncbi.nlm.nih.gov/pubmed/37623997
http://dx.doi.org/10.3390/pathogens12081037
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