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Epilepsy Due to Solitary Calcified Cysticercus Granuloma
The calcified stage of the neurocysticercosis (NCC) is the common cause of acquired epilepsy in low and middle income countries in people aged > 20 years. Approximately 30% of adult onset seizures and epilepsy are attributable to NCC. In India and some of the Latin American countries, epilepsy du...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459524/ https://www.ncbi.nlm.nih.gov/pubmed/37623997 http://dx.doi.org/10.3390/pathogens12081037 |
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author | Murthy, Jagarlapudi M. K. |
author_facet | Murthy, Jagarlapudi M. K. |
author_sort | Murthy, Jagarlapudi M. K. |
collection | PubMed |
description | The calcified stage of the neurocysticercosis (NCC) is the common cause of acquired epilepsy in low and middle income countries in people aged > 20 years. Approximately 30% of adult onset seizures and epilepsy are attributable to NCC. In India and some of the Latin American countries, epilepsy due to solitary calcified NCC is the common adult onset epilepsy. The current evidence suggests that the calcified cysticercus granuloma is probably the epileptogenic focus. The mechanisms involved in the epileptogenic process are not well understood; Focal-onset seizures with or without impaired awareness are the common seizure type. Focal-onset seizure can evolve to bilateral tonic-clonic seizure. Seizure outcome with anti-seizure medication, most often with monotherapy, is very good. The seizure disorders associated with various stages of NCC can be preventable. |
format | Online Article Text |
id | pubmed-10459524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104595242023-08-27 Epilepsy Due to Solitary Calcified Cysticercus Granuloma Murthy, Jagarlapudi M. K. Pathogens Perspective The calcified stage of the neurocysticercosis (NCC) is the common cause of acquired epilepsy in low and middle income countries in people aged > 20 years. Approximately 30% of adult onset seizures and epilepsy are attributable to NCC. In India and some of the Latin American countries, epilepsy due to solitary calcified NCC is the common adult onset epilepsy. The current evidence suggests that the calcified cysticercus granuloma is probably the epileptogenic focus. The mechanisms involved in the epileptogenic process are not well understood; Focal-onset seizures with or without impaired awareness are the common seizure type. Focal-onset seizure can evolve to bilateral tonic-clonic seizure. Seizure outcome with anti-seizure medication, most often with monotherapy, is very good. The seizure disorders associated with various stages of NCC can be preventable. MDPI 2023-08-14 /pmc/articles/PMC10459524/ /pubmed/37623997 http://dx.doi.org/10.3390/pathogens12081037 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Perspective Murthy, Jagarlapudi M. K. Epilepsy Due to Solitary Calcified Cysticercus Granuloma |
title | Epilepsy Due to Solitary Calcified Cysticercus Granuloma |
title_full | Epilepsy Due to Solitary Calcified Cysticercus Granuloma |
title_fullStr | Epilepsy Due to Solitary Calcified Cysticercus Granuloma |
title_full_unstemmed | Epilepsy Due to Solitary Calcified Cysticercus Granuloma |
title_short | Epilepsy Due to Solitary Calcified Cysticercus Granuloma |
title_sort | epilepsy due to solitary calcified cysticercus granuloma |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459524/ https://www.ncbi.nlm.nih.gov/pubmed/37623997 http://dx.doi.org/10.3390/pathogens12081037 |
work_keys_str_mv | AT murthyjagarlapudimk epilepsyduetosolitarycalcifiedcysticercusgranuloma |