Cardiomyocyte-Targeting Peptide to Deliver Amiodarone

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Background: Amiodarone is underutilized due to significant off-target toxicities. We hypothesized that targeted delivery to the heart would lead to the lowering of the dose by utilizing a cardiomyocyte-targeting peptide (CTP), a cell-penetrating peptide identified by our prior phage display work. Me...

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Detalles Bibliográficos
Autores principales: Zahid, Maliha, Weber, Beth, Yurko, Ray, Islam, Kazi, Agrawal, Vaishavi, Lopuszynski, Jack, Yagi, Hisato, Salama, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459552/
https://www.ncbi.nlm.nih.gov/pubmed/37631321
http://dx.doi.org/10.3390/pharmaceutics15082107
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