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Antibody-Drug Conjugates in Solid Tumor Oncology: An Effectiveness Payday with a Targeted Payload

Antibody–drug conjugates (ADCs) are at the forefront of the drug development revolution occurring in oncology. Formed from three main components—an antibody, a linker molecule, and a cytotoxic agent (“payload”), ADCs have the unique ability to deliver cytotoxic agents to cells expressing a specific...

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Detalles Bibliográficos
Autores principales: Kondrashov, Aleksei, Sapkota, Surendra, Sharma, Aditya, Riano, Ivy, Kurzrock, Razelle, Adashek, Jacob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459723/
https://www.ncbi.nlm.nih.gov/pubmed/37631374
http://dx.doi.org/10.3390/pharmaceutics15082160