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Modification of Poly(Glycerol Adipate) with Tocopherol and Cholesterol Modulating Nanoparticle Self-Assemblies and Cellular Responses of Triple-Negative Breast Cancer Cells to SN-38 Delivery

This study aimed to fabricate new variations of glycerol-based polyesters by grafting poly(glycerol adipate) (PGA) with hydrophobic bioactive moieties, tocopherol (TOC), and cholesterol (CHO). Their effects on nanoparticle (NP) formation, drug release, and cellular responses in cancer and normal cel...

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Detalles Bibliográficos
Autores principales: Suksiriworapong, Jiraphong, Achayawat, Chittin, Juangrattanakamjorn, Phutthikom, Taresco, Vincenzo, Crucitti, Valentina Cuzzucoli, Sakchaisri, Krisada, Bunsupa, Somnuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459774/
https://www.ncbi.nlm.nih.gov/pubmed/37631315
http://dx.doi.org/10.3390/pharmaceutics15082100

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