Theoretical Assessment of the Ligand/Metal/Quadruplex Recognition in the Non-Canonical Nucleic Acids Structures

Quadruplexes (GQs), peculiar DNA/RNA motifs concentrated in specific genomic regions, play a vital role in biological processes including telomere stability and, hence, represent promising targets for anticancer therapy. GQs are formed by folding guanine-rich sequences into square planar G-tetrads w...

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Detalles Bibliográficos
Autores principales: Kircheva, Nikoleta, Dobrev, Stefan, Petkova, Vladislava, Bakalova, Snezhana, Kaneti, Jose, Angelova, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459790/
https://www.ncbi.nlm.nih.gov/pubmed/37630360
http://dx.doi.org/10.3390/molecules28166109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459790/
https://www.ncbi.nlm.nih.gov/pubmed/37630360
http://dx.doi.org/10.3390/molecules28166109

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