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Increased Free Radical Generation during the Interaction of a Quinone-Quinoline Chelator with Metal Ions and the Enhancing Effect of Light

Schiff bases and similar molecules forming metal complexes may cause redox effects, which may also be influenced by light. Anthraquinones such as doxorubicin and idarubicin are widely used antitumor agents, which can generate reactive oxygen species (ROS), stimulated by both the presence of iron and...

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Detalles Bibliográficos
Autores principales: Selyutina, Olga Yu., Babenko, Simon V., Slepneva, Irina A., Polyakov, Nikolay E., Kontoghiorghes, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459951/
https://www.ncbi.nlm.nih.gov/pubmed/37631031
http://dx.doi.org/10.3390/ph16081116

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