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Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study
Objective: To describe the frequency of malnutrition in older patients with rheumatoid arthritis (RA) and investigate associated risk factors. Methods: This multicenter, cross-sectional study included participants aged ≥65 years who met the 2010 ACR/EULAR criteria for RA. Nutritional status was asse...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460011/ https://www.ncbi.nlm.nih.gov/pubmed/37630691 http://dx.doi.org/10.3390/nu15163500 |
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author | Cano-García, Laura Redondo-Rodríguez, Rocío Manrique-Arija, Sara Domínguez-Quesada, Carmen Crisóstomo Vacas, Juan Armenteros-Ortiz, Pedro Ruiz-Vilchez, Desiree Martín-Martín, José María García-Studer, Aimara Ortiz-Márquez, Fernando Mena-Vázquez, Natalia Fernández-Nebro, Antonio |
author_facet | Cano-García, Laura Redondo-Rodríguez, Rocío Manrique-Arija, Sara Domínguez-Quesada, Carmen Crisóstomo Vacas, Juan Armenteros-Ortiz, Pedro Ruiz-Vilchez, Desiree Martín-Martín, José María García-Studer, Aimara Ortiz-Márquez, Fernando Mena-Vázquez, Natalia Fernández-Nebro, Antonio |
author_sort | Cano-García, Laura |
collection | PubMed |
description | Objective: To describe the frequency of malnutrition in older patients with rheumatoid arthritis (RA) and investigate associated risk factors. Methods: This multicenter, cross-sectional study included participants aged ≥65 years who met the 2010 ACR/EULAR criteria for RA. Nutritional status was assessed using the Mini Nutritional Assessment Short Form (MNA-SF) and based on variables, such as albumin level, the Geriatric Nutritional Risk Index (GNRI), and vitamin D. Data were also collected on epidemiological variables, inflammatory disease activity, quality of life, physical function, and frailty. Multivariate models were used to study factors associated with nutritional status. Results: The study population comprised 76 RA patients aged ≥65 years, of whom 68.4% had a normal nutritional status, and 31.5% had an impaired nutritional status: 28.9% were at risk of malnutrition, and 2.6% were malnourished. Additionally, 10% had albumin levels <3.8 g/L. Patients with impaired nutritional status had poorer quality of life and physical function. The factors associated with compromised nutritional status (OR [95% CI]) were age (1.0 [1.0–1.1]; p = 0.035), DAS28-ESR (1.8 [1.0–3.2]; p = 0.024), and EuroQoL-5D-5L (0.9 [0.9–0.9]; p = 0.040). Furthermore, the GNRI was associated with the MNA score (0.06 [0.0–0.1]; p = 0.014). Conclusions: Approximately one-third of older patients with RA have impaired nutritional status. Older age, higher inflammatory disease activity, and decreased quality of life are associated with impaired nutritional status. The MNA and GNRI are valuable tools for assessing the nutritional status of patients with RA. |
format | Online Article Text |
id | pubmed-10460011 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104600112023-08-27 Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study Cano-García, Laura Redondo-Rodríguez, Rocío Manrique-Arija, Sara Domínguez-Quesada, Carmen Crisóstomo Vacas, Juan Armenteros-Ortiz, Pedro Ruiz-Vilchez, Desiree Martín-Martín, José María García-Studer, Aimara Ortiz-Márquez, Fernando Mena-Vázquez, Natalia Fernández-Nebro, Antonio Nutrients Article Objective: To describe the frequency of malnutrition in older patients with rheumatoid arthritis (RA) and investigate associated risk factors. Methods: This multicenter, cross-sectional study included participants aged ≥65 years who met the 2010 ACR/EULAR criteria for RA. Nutritional status was assessed using the Mini Nutritional Assessment Short Form (MNA-SF) and based on variables, such as albumin level, the Geriatric Nutritional Risk Index (GNRI), and vitamin D. Data were also collected on epidemiological variables, inflammatory disease activity, quality of life, physical function, and frailty. Multivariate models were used to study factors associated with nutritional status. Results: The study population comprised 76 RA patients aged ≥65 years, of whom 68.4% had a normal nutritional status, and 31.5% had an impaired nutritional status: 28.9% were at risk of malnutrition, and 2.6% were malnourished. Additionally, 10% had albumin levels <3.8 g/L. Patients with impaired nutritional status had poorer quality of life and physical function. The factors associated with compromised nutritional status (OR [95% CI]) were age (1.0 [1.0–1.1]; p = 0.035), DAS28-ESR (1.8 [1.0–3.2]; p = 0.024), and EuroQoL-5D-5L (0.9 [0.9–0.9]; p = 0.040). Furthermore, the GNRI was associated with the MNA score (0.06 [0.0–0.1]; p = 0.014). Conclusions: Approximately one-third of older patients with RA have impaired nutritional status. Older age, higher inflammatory disease activity, and decreased quality of life are associated with impaired nutritional status. The MNA and GNRI are valuable tools for assessing the nutritional status of patients with RA. MDPI 2023-08-08 /pmc/articles/PMC10460011/ /pubmed/37630691 http://dx.doi.org/10.3390/nu15163500 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cano-García, Laura Redondo-Rodríguez, Rocío Manrique-Arija, Sara Domínguez-Quesada, Carmen Crisóstomo Vacas, Juan Armenteros-Ortiz, Pedro Ruiz-Vilchez, Desiree Martín-Martín, José María García-Studer, Aimara Ortiz-Márquez, Fernando Mena-Vázquez, Natalia Fernández-Nebro, Antonio Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
title | Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
title_full | Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
title_fullStr | Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
title_full_unstemmed | Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
title_short | Prevalence of Malnutrition and Associated Factors in Older Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
title_sort | prevalence of malnutrition and associated factors in older patients with rheumatoid arthritis: a cross-sectional study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460011/ https://www.ncbi.nlm.nih.gov/pubmed/37630691 http://dx.doi.org/10.3390/nu15163500 |
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