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Abiraterone-Induced Hypokalemia: A Case Report

Abiraterone, an androgen biosynthesis inhibitor drug approved by the Food and Drug Administration (FDA) in 2011 for the treatment of metastatic prostate cancer, has seen an increase in prescriptions over the years, owing largely to the aging population and the association of prostate cancer with inc...

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Detalles Bibliográficos
Autores principales: Nkwocha, Bernard I, Singh, Meenu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460115/
https://www.ncbi.nlm.nih.gov/pubmed/37637533
http://dx.doi.org/10.7759/cureus.42533
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author Nkwocha, Bernard I
Singh, Meenu
author_facet Nkwocha, Bernard I
Singh, Meenu
author_sort Nkwocha, Bernard I
collection PubMed
description Abiraterone, an androgen biosynthesis inhibitor drug approved by the Food and Drug Administration (FDA) in 2011 for the treatment of metastatic prostate cancer, has seen an increase in prescriptions over the years, owing largely to the aging population and the association of prostate cancer with increasing age. As the rate of abiraterone prescription increases, it is important for physicians to be aware of its adverse effects profile to improve patient outcomes. This case report explains the mechanism, clinical presentation, and management of abiraterone-induced hypokalemia in a 67-year-old male with prostate cancer and highlights the importance of close monitoring and management of electrolyte levels for patients on abiraterone.
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spelling pubmed-104601152023-08-27 Abiraterone-Induced Hypokalemia: A Case Report Nkwocha, Bernard I Singh, Meenu Cureus Urology Abiraterone, an androgen biosynthesis inhibitor drug approved by the Food and Drug Administration (FDA) in 2011 for the treatment of metastatic prostate cancer, has seen an increase in prescriptions over the years, owing largely to the aging population and the association of prostate cancer with increasing age. As the rate of abiraterone prescription increases, it is important for physicians to be aware of its adverse effects profile to improve patient outcomes. This case report explains the mechanism, clinical presentation, and management of abiraterone-induced hypokalemia in a 67-year-old male with prostate cancer and highlights the importance of close monitoring and management of electrolyte levels for patients on abiraterone. Cureus 2023-07-27 /pmc/articles/PMC10460115/ /pubmed/37637533 http://dx.doi.org/10.7759/cureus.42533 Text en Copyright © 2023, Nkwocha et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Urology
Nkwocha, Bernard I
Singh, Meenu
Abiraterone-Induced Hypokalemia: A Case Report
title Abiraterone-Induced Hypokalemia: A Case Report
title_full Abiraterone-Induced Hypokalemia: A Case Report
title_fullStr Abiraterone-Induced Hypokalemia: A Case Report
title_full_unstemmed Abiraterone-Induced Hypokalemia: A Case Report
title_short Abiraterone-Induced Hypokalemia: A Case Report
title_sort abiraterone-induced hypokalemia: a case report
topic Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460115/
https://www.ncbi.nlm.nih.gov/pubmed/37637533
http://dx.doi.org/10.7759/cureus.42533
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