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Branched Multimeric Peptides as Affinity Reagents for the Detection of α-Klotho Protein

α-Klotho, an aging-related protein found in the kidney, parathyroid gland, and choroid plexus, acts as an essential co-receptor with the fibroblast growth factor 23 receptor complex to regulate serum phosphate and vitamin D levels. Decreased levels of α-Klotho are a hallmark of age-associated diseas...

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Detalles Bibliográficos
Autores principales: Ye, Xiyun, Zhang, Peiyuan, Wang, John C. K., Smith, Corey L., Sousa, Silvino, Loas, Andrei, Eaton, Dan L., López, Magdalena Preciado, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460140/
https://www.ncbi.nlm.nih.gov/pubmed/36894520
http://dx.doi.org/10.1002/anie.202300289