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Branched Multimeric Peptides as Affinity Reagents for the Detection of α-Klotho Protein
α-Klotho, an aging-related protein found in the kidney, parathyroid gland, and choroid plexus, acts as an essential co-receptor with the fibroblast growth factor 23 receptor complex to regulate serum phosphate and vitamin D levels. Decreased levels of α-Klotho are a hallmark of age-associated diseas...
Autores principales: | Ye, Xiyun, Zhang, Peiyuan, Wang, John C. K., Smith, Corey L., Sousa, Silvino, Loas, Andrei, Eaton, Dan L., López, Magdalena Preciado, Pentelute, Bradley L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460140/ https://www.ncbi.nlm.nih.gov/pubmed/36894520 http://dx.doi.org/10.1002/anie.202300289 |
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