Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient

A 72-year-old man presented to our clinic with hypertension. Arterial stiffness evaluated by cardio ankle vascular index (CAVI) was markedly increased at 13.5. We treated him using 80 mg/day of valsartan for three months. CAVI was decreased from 13.5 to 13.0. However, his BP fluctuations were still...

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Autores principales: Shimizu, Kazuhiro, Tabata, Tsuyoshi, Iwakawa, Masahiro, Sato, Shuji, Kinoshita, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460203/
https://www.ncbi.nlm.nih.gov/pubmed/37636989
http://dx.doi.org/10.2147/IMCRJ.S422196
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author Shimizu, Kazuhiro
Tabata, Tsuyoshi
Iwakawa, Masahiro
Sato, Shuji
Kinoshita, Toshio
author_facet Shimizu, Kazuhiro
Tabata, Tsuyoshi
Iwakawa, Masahiro
Sato, Shuji
Kinoshita, Toshio
author_sort Shimizu, Kazuhiro
collection PubMed
description A 72-year-old man presented to our clinic with hypertension. Arterial stiffness evaluated by cardio ankle vascular index (CAVI) was markedly increased at 13.5. We treated him using 80 mg/day of valsartan for three months. CAVI was decreased from 13.5 to 13.0. However, his BP fluctuations were still high. We changed the treatment to angiotensin receptor-neprilysin inhibitor (ARNI) with increasing doses up to 400 mg. Independent of the change in blood pressure at the time of measurement, CAVI improved with ARNI dose. Hypertension treatment with an awareness of the cardio-vascular interaction might be a possibility prevents future heart failure development effectively.
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spelling pubmed-104602032023-08-27 Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient Shimizu, Kazuhiro Tabata, Tsuyoshi Iwakawa, Masahiro Sato, Shuji Kinoshita, Toshio Int Med Case Rep J Case Report A 72-year-old man presented to our clinic with hypertension. Arterial stiffness evaluated by cardio ankle vascular index (CAVI) was markedly increased at 13.5. We treated him using 80 mg/day of valsartan for three months. CAVI was decreased from 13.5 to 13.0. However, his BP fluctuations were still high. We changed the treatment to angiotensin receptor-neprilysin inhibitor (ARNI) with increasing doses up to 400 mg. Independent of the change in blood pressure at the time of measurement, CAVI improved with ARNI dose. Hypertension treatment with an awareness of the cardio-vascular interaction might be a possibility prevents future heart failure development effectively. Dove 2023-08-22 /pmc/articles/PMC10460203/ /pubmed/37636989 http://dx.doi.org/10.2147/IMCRJ.S422196 Text en © 2023 Shimizu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Shimizu, Kazuhiro
Tabata, Tsuyoshi
Iwakawa, Masahiro
Sato, Shuji
Kinoshita, Toshio
Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient
title Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient
title_full Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient
title_fullStr Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient
title_full_unstemmed Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient
title_short Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient
title_sort sacubitril/valsartan shows improvement of the cardio-ankle vascular index in a hypertensive patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460203/
https://www.ncbi.nlm.nih.gov/pubmed/37636989
http://dx.doi.org/10.2147/IMCRJ.S422196
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