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Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy
SIGNIFICANCE: Peripheral nerves are viscoelastic tissues with unique elastic characteristics. Imaging of peripheral nerve elasticity is important in medicine, particularly in the context of nerve injury and repair. Elasticity imaging techniques provide information about the mechanical properties of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Photo-Optical Instrumentation Engineers
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460255/ https://www.ncbi.nlm.nih.gov/pubmed/37635849 http://dx.doi.org/10.1117/1.NPh.10.3.035007 |
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author | Cheburkanov, Vsevolod Du, Junwei Brogan, David M. Berezin, Mikhail Y. Yakovlev, Vladislav V. |
author_facet | Cheburkanov, Vsevolod Du, Junwei Brogan, David M. Berezin, Mikhail Y. Yakovlev, Vladislav V. |
author_sort | Cheburkanov, Vsevolod |
collection | PubMed |
description | SIGNIFICANCE: Peripheral nerves are viscoelastic tissues with unique elastic characteristics. Imaging of peripheral nerve elasticity is important in medicine, particularly in the context of nerve injury and repair. Elasticity imaging techniques provide information about the mechanical properties of peripheral nerves, which can be useful in identifying areas of nerve damage or compression, as well as assessing the success of nerve repair procedures. AIM: We aim to assess the feasibility of Brillouin microspectroscopy for peripheral nerve imaging of elasticity, with the ultimate goal of developing a new diagnostic tool for peripheral nerve injury in vivo. APPROACH: Viscoelastic properties of the peripheral nerve were evaluated with Brillouin imaging spectroscopy. RESULTS: An external stress exerted on the fixed nerve resulted in a Brillouin shift. Quantification of the shift enabled correlation of the Brillouin parameters with nerve elastic properties. CONCLUSIONS: Brillouin microscopy provides sufficient sensitivity to assess viscoelastic properties of peripheral nerves. |
format | Online Article Text |
id | pubmed-10460255 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Society of Photo-Optical Instrumentation Engineers |
record_format | MEDLINE/PubMed |
spelling | pubmed-104602552023-08-27 Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy Cheburkanov, Vsevolod Du, Junwei Brogan, David M. Berezin, Mikhail Y. Yakovlev, Vladislav V. Neurophotonics Research Papers SIGNIFICANCE: Peripheral nerves are viscoelastic tissues with unique elastic characteristics. Imaging of peripheral nerve elasticity is important in medicine, particularly in the context of nerve injury and repair. Elasticity imaging techniques provide information about the mechanical properties of peripheral nerves, which can be useful in identifying areas of nerve damage or compression, as well as assessing the success of nerve repair procedures. AIM: We aim to assess the feasibility of Brillouin microspectroscopy for peripheral nerve imaging of elasticity, with the ultimate goal of developing a new diagnostic tool for peripheral nerve injury in vivo. APPROACH: Viscoelastic properties of the peripheral nerve were evaluated with Brillouin imaging spectroscopy. RESULTS: An external stress exerted on the fixed nerve resulted in a Brillouin shift. Quantification of the shift enabled correlation of the Brillouin parameters with nerve elastic properties. CONCLUSIONS: Brillouin microscopy provides sufficient sensitivity to assess viscoelastic properties of peripheral nerves. Society of Photo-Optical Instrumentation Engineers 2023-08-26 2023-07 /pmc/articles/PMC10460255/ /pubmed/37635849 http://dx.doi.org/10.1117/1.NPh.10.3.035007 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. |
spellingShingle | Research Papers Cheburkanov, Vsevolod Du, Junwei Brogan, David M. Berezin, Mikhail Y. Yakovlev, Vladislav V. Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy |
title | Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy |
title_full | Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy |
title_fullStr | Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy |
title_full_unstemmed | Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy |
title_short | Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy |
title_sort | toward peripheral nerve mechanical characterization using brillouin imaging spectroscopy |
topic | Research Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460255/ https://www.ncbi.nlm.nih.gov/pubmed/37635849 http://dx.doi.org/10.1117/1.NPh.10.3.035007 |
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