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Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies

Aortic valve degeneration (AVD) is a life-threatening condition that has no medical treatment and lacks individual therapies. Although extensively studied with standard approaches, aetiologies behind AVD are unclear. We compared abundances of extracellular matrix (ECM) proteins from excised valve ti...

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Detalles Bibliográficos
Autores principales:	Beusch, Christian M., Simonson, Oscar E., Wedin, Johan O., Sabatier, Pierre, Felldin, Ulrika, Kadekar, Sandeep, Österholm, Cecilia, Végvári, Ákos, Zubarev, Roman A., Fromell, Karin, Nilson, Bo, James, Stefan, Ståhle, Elisabeth, Grinnemo, Karl-Henrik, Rodin, Sergey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460373/ https://www.ncbi.nlm.nih.gov/pubmed/37632572 http://dx.doi.org/10.1007/s00018-023-04926-1

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