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The stem region of group A transferase is crucial for its specificity, and its alteration promotes heterologous Forssman synthase activity

Some stem region mutants of human blood group A transferase (hAT) possess Forssman synthase (FS) activity, but very little is known about the mechanisms responsible for this enzymatic crosstalk. We performed confocal microscopy and image analysis to determine whether different intra-Golgi localizati...

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Detalles Bibliográficos
Autores principales: Cid, Emili, Yamamoto, Miyako, Barrero, Laura, Yamamoto, Fumiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460411/
https://www.ncbi.nlm.nih.gov/pubmed/37634031
http://dx.doi.org/10.1038/s41598-023-40900-4

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