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FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner

Ferroptosis, a type of cell death induced by lipid peroxidation, has emerged as a novel anti-cancer strategy. Cancer cells frequently acquire resistance to ferroptosis. However, the underlying mechanisms are poorly understood. To address this issue, we conducted a thorough investigation of the genom...

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Detalles Bibliográficos
Autores principales: Kim, Jong Woo, Kim, Min-Ju, Han, Tae-Hee, Lee, Ji-Yoon, Kim, Sangok, Kim, Hyerin, Oh, Kyoung-Jin, Kim, Won Kon, Han, Baek-Soo, Bae, Kwang-Hee, Ban, Hyun Seung, Bae, Soo Han, Lee, Sang Chul, Lee, Haeseung, Lee, Eun-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460413/
https://www.ncbi.nlm.nih.gov/pubmed/37633973
http://dx.doi.org/10.1038/s41419-023-06070-x