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Tamoxifen associated to the conservative CKD treatment promoted additional antifibrotic effects on experimental hypertensive nephrosclerosis

CKD progression depends on the activation of an intricate set of hemodynamic and inflammatory mechanisms, promoting renal leukocyte infiltration, inflammation and fibrosis, leading to renal function loss. There are currently no specific drugs to detain renal fibrogenesis, which is a common end-point...

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Detalles Bibliográficos
Autores principales: Fanelli, Camilla, Francini, Ana L. R., Celestrino, Giovanna A., Teles, Flávio, Barbosa, Ana P., Noda, Paloma, Iannuzzi, Leandro R., Guzzo, Cristiane R., Ornellas, Felipe M., Noronha, Irene L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460450/
https://www.ncbi.nlm.nih.gov/pubmed/37633958
http://dx.doi.org/10.1038/s41598-023-39299-9