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Tamoxifen associated to the conservative CKD treatment promoted additional antifibrotic effects on experimental hypertensive nephrosclerosis
CKD progression depends on the activation of an intricate set of hemodynamic and inflammatory mechanisms, promoting renal leukocyte infiltration, inflammation and fibrosis, leading to renal function loss. There are currently no specific drugs to detain renal fibrogenesis, which is a common end-point...
Autores principales: | Fanelli, Camilla, Francini, Ana L. R., Celestrino, Giovanna A., Teles, Flávio, Barbosa, Ana P., Noda, Paloma, Iannuzzi, Leandro R., Guzzo, Cristiane R., Ornellas, Felipe M., Noronha, Irene L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460450/ https://www.ncbi.nlm.nih.gov/pubmed/37633958 http://dx.doi.org/10.1038/s41598-023-39299-9 |
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