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Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review

Preterm labor, regarded as the onset of labor before 37 weeks of gestation, is a highly prevalent issue in obstetrics with repercussions for neonatal health. This review article presents an in-depth analysis of the alliance between serum magnesium levels and preterm labor. The review explores the ph...

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Autores principales: Deeksha, H S, Pajai, Sandhya, Cherukuri, Srinidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460502/
https://www.ncbi.nlm.nih.gov/pubmed/37641740
http://dx.doi.org/10.7759/cureus.42602
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author Deeksha, H S
Pajai, Sandhya
Cherukuri, Srinidhi
author_facet Deeksha, H S
Pajai, Sandhya
Cherukuri, Srinidhi
author_sort Deeksha, H S
collection PubMed
description Preterm labor, regarded as the onset of labor before 37 weeks of gestation, is a highly prevalent issue in obstetrics with repercussions for neonatal health. This review article presents an in-depth analysis of the alliance between serum magnesium levels and preterm labor. The review explores the physiological roles of magnesium right through pregnancy, including its significance for energy metabolism, smooth muscle contraction, deoxyribonucleic acid (DNA), and protein synthesis. It addresses cellular transport and the homeostasis of magnesium. The pathophysiological processes encompassing inflammation, oxidative stress, calcium regulation, smooth muscle contractility, and neuroendocrine pathways are investigated. The review evaluates epidemiological studies investigating the alliance between serum magnesium levels and preterm labor. The review incorporates an assortment of study varieties, such as observational studies, case-control studies, prospective cohort studies, and meta-analyses. In the course of reviewing the prognostic relevance of serum magnesium levels in premature labor, therapeutic implications involving diagnostic precision, prognostic significance, and therapeutic response assessment have additionally been addressed. Therapeutic interventions targeting magnesium levels, such as magnesium supplementation, tocolytic therapy, and the role of magnesium in antenatal corticosteroid administration, are explored. This review provides an in-depth evaluation of the correlation between serum magnesium levels and preterm labor, stressing its therapeutic significance and repercussions for future research and treatment strategies.
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spelling pubmed-104605022023-08-28 Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review Deeksha, H S Pajai, Sandhya Cherukuri, Srinidhi Cureus Medical Education Preterm labor, regarded as the onset of labor before 37 weeks of gestation, is a highly prevalent issue in obstetrics with repercussions for neonatal health. This review article presents an in-depth analysis of the alliance between serum magnesium levels and preterm labor. The review explores the physiological roles of magnesium right through pregnancy, including its significance for energy metabolism, smooth muscle contraction, deoxyribonucleic acid (DNA), and protein synthesis. It addresses cellular transport and the homeostasis of magnesium. The pathophysiological processes encompassing inflammation, oxidative stress, calcium regulation, smooth muscle contractility, and neuroendocrine pathways are investigated. The review evaluates epidemiological studies investigating the alliance between serum magnesium levels and preterm labor. The review incorporates an assortment of study varieties, such as observational studies, case-control studies, prospective cohort studies, and meta-analyses. In the course of reviewing the prognostic relevance of serum magnesium levels in premature labor, therapeutic implications involving diagnostic precision, prognostic significance, and therapeutic response assessment have additionally been addressed. Therapeutic interventions targeting magnesium levels, such as magnesium supplementation, tocolytic therapy, and the role of magnesium in antenatal corticosteroid administration, are explored. This review provides an in-depth evaluation of the correlation between serum magnesium levels and preterm labor, stressing its therapeutic significance and repercussions for future research and treatment strategies. Cureus 2023-07-28 /pmc/articles/PMC10460502/ /pubmed/37641740 http://dx.doi.org/10.7759/cureus.42602 Text en Copyright © 2023, Deeksha et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Education
Deeksha, H S
Pajai, Sandhya
Cherukuri, Srinidhi
Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review
title Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review
title_full Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review
title_fullStr Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review
title_full_unstemmed Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review
title_short Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review
title_sort study based on the alliance between serum magnesium levels and preterm labor: an inclusive review
topic Medical Education
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460502/
https://www.ncbi.nlm.nih.gov/pubmed/37641740
http://dx.doi.org/10.7759/cureus.42602
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