Cargando…

Association of Met420del Variant of Metformin Transporter Gene SLC22A1 with Metformin Treatment Response in Ethiopian Patients with Type 2 Diabetes

OBJECTIVE: This study aimed to evaluate whether the M420del variants of SLC22A1 (rs72552763) is associated with metformin treatment response in Ethiopian patients with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS: A prospective observational cohort study was conducted on 86 patients with T2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Degaga, Abraham, Sirgu, Sisay, Huri, Hasniza Zaman, Sim, Maw Shin, Kebede, Tedla, Tegene, Birhanemeskel, Loganadan, Navin Kumar, Engidawork, Ephrem, Shibeshi, Workineh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460611/ https://www.ncbi.nlm.nih.gov/pubmed/37641646 http://dx.doi.org/10.2147/DMSO.S426632

Ejemplares similares

Evaluation of the antidiarrheal activity of the leaf extracts of Myrtus communis Linn (Myrtaceae) in mice model
por: Sisay, Mekonnen, et al.
Publicado: (2017)

Prevalence and predictors of glucose metabolism disorders among People Living with HIV on combination antiretroviral therapy
por: Tadesse, Wondmagegn Tamiru, et al.
Publicado: (2022)

Explorative Analysis of Treatment Outcomes of Levofloxacin- and Moxifloxacin-Based Regimens and Outcome Predictors in Ethiopian MDR-TB Patients: A Prospective Observational Cohort Study
por: Sidamo, Temesgen, et al.
Publicado: (2021)

Evaluation of the anti-diarrheal activity of the leaf extract of Croton macrostachyus Hocsht. ex Del. (Euphorbiaceae) in mice model
por: Degu, Amsalu, et al.
Publicado: (2016)

Allele Frequency of SLC22A1 Met420del Metformin Main Transporter Encoding Gene among Javanese-Indonesian Population
por: Ningrum, Vitarani DA, et al.
Publicado: (2019)

Efficacy and safety of artemisinin-based combination therapies for the treatment of uncomplicated malaria in pediatrics: a systematic review and meta-analysis
por: Shibeshi, Workineh, et al.
Publicado: (2021)

Efficacy and Safety of Artemisinin-Based Combination Therapy for the Treatment of Uncomplicated Malaria in Pregnant Women: A Systematic Review and Meta-Analysis
por: Shibeshi, Workineh, et al.
Publicado: (2021)

Population Pharmacokinetics of Levofloxacin and Moxifloxacin, and the Probability of Target Attainment in Ethiopian Patients with Multidrug-Resistant Tuberculosis
por: Sidamo, Temesgen, et al.
Publicado: (2022)

Predicting the risk of atherosclerotic cardiovascular disease among adults living with HIV/AIDS in Addis Ababa, Ethiopia: A hospital-based study
por: Woldu, Minyahil, et al.
Publicado: (2021)

Biomarkers and Prevalence of Cardiometabolic Syndrome Among People Living With HIV/AIDS, Addis Ababa, Ethiopia: A Hospital-Based Study
por: Woldu, Minyahil, et al.
Publicado: (2022)

Cardiometabolic syndrome in HIV-positive and HIV-negative patients at Zewditu Memorial Hospital, Addis Ababa, Ethiopia: a comparative cohort study
por: Woldu, Minyahil, et al.
Publicado: (2022)

Reproducibility of malaria sporozoite challenge model in humans for evaluating efficacy of vaccines and drugs: a systematic review
por: Shibeshi, Workineh, et al.
Publicado: (2021)

Impact of medication therapy management service on selected clinical and humanistic outcomes in the ambulatory diabetes patients of Tikur Anbessa Specialist Hospital, Addis Ababa, Ethiopia
por: Negash, Zenebe, et al.
Publicado: (2021)

Pharmacokinetics and Metabolomic Profiling of Metformin and Andrographis paniculata: A Protocol for a Crossover Randomised Controlled Trial
por: Tee, Khim Boon, et al.
Publicado: (2022)

Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells
por: Kahaliw, Wubayehu, et al.
Publicado: (2018)

Drug therapy problems, medication adherence and treatment satisfaction among diabetic patients on follow-up care at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
por: Demoz, Gebre Teklemariam, et al.
Publicado: (2019)

CYP3A and CYP2B6 Genotype Predicts Glucose Metabolism Disorder among HIV Patients on Long-Term Efavirenz-Based ART: A Case-Control Study
por: Tadesse, Wondmagegn Tamiru, et al.
Publicado: (2022)

Surgical Antimicrobial Prophylaxis and Incidence of Surgical Site Infections at Ethiopian Tertiary-Care Teaching Hospital
por: Alamrew, Kerebih, et al.
Publicado: (2019)

In vitro antibacterial and antifungal activities of extracts and fractions of leaves of Ricinus communis Linn against selected pathogens
por: Kebede, Bedaso, et al.
Publicado: (2022)

Evaluation of the antimycobacterial activity of crude extracts and solvent fractions of selected Ethiopian medicinal plants
por: Kahaliw, Wubayehu, et al.
Publicado: (2017)

Prevalence and determinants of non-adherence to Imatinib in the first 3-months treatment among newly diagnosed Ethiopian’s with chronic myeloid leukemia
por: Mulu Fentie, Atalay, et al.
Publicado: (2019)

Variants of SLC2A10 may be Linked to Poor Response to Metformin
por: Paz-Pacheco, Elizabeth, et al.
Publicado: (2022)

Current status, challenges and the way forward for clinical pharmacy service in Ethiopian public hospitals
por: Bilal, Arebu Issa, et al.
Publicado: (2017)

Barriers and facilitators to adherence to anti-diabetic medications: Ethiopian patients’ perspectives
por: Habte, Bruck M., et al.
Publicado: (2017)

Ethiopian patients’ perceptions of anti-diabetic medications: implications for diabetes education
por: Habte, Bruck Messele, et al.
Publicado: (2017)

Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer
por: Yang, Jingjing, et al.
Publicado: (2021)

Knowledge, attitude and practices on cervical cancer screening among undergraduate female students in University of Gondar, Northwest Ethiopia: an institution based cross sectional study
por: Getaneh, Alem, et al.
Publicado: (2021)

Sex Differences in Neuropathy: The Paradigmatic Case of MetFormin
por: De Angelis, Federica, et al.
Publicado: (2022)

In Vivo anti-trypanosomal activity of dichloromethane and methanol crude leaf extracts of Dovyalis abyssinica (Salicaceae) against Trypanosoma congolense
por: Tadesse, Belay, et al.
Publicado: (2015)

Pharmacokinetic study of metformin to compare a voglibose/metformin fixed-dose combination with coadministered voglibose and metformin
por: Choi, Hyang-Ki, et al.
Publicado: (2015)

Metformin allergy
por: Wiwanitkit, Viroj
Publicado: (2011)

Metformin - For the dermatologist
por: Bubna, Aditya Kumar
Publicado: (2016)

Anatomographic Variants of Sphenoid Sinus in Ethiopian Population
por: Degaga, Tizita K., et al.
Publicado: (2020)

Association of SLC22A1, SLC22A2, SLC47A1, and SLC47A2 Polymorphisms with Metformin Efficacy in Type 2 Diabetic Patients
por: Chen, Peixian, et al.
Publicado: (2022)

Metformin Beyond Diabetes: Pleiotropic Benefits of Metformin in Attenuation of Atherosclerosis
por: Forouzandeh, Farshad, et al.
Publicado: (2014)

Effects of Metformin, Metformin Plus Rosiglitazone, and Metformin Plus Lifestyle on Insulin Sensitivity and β-Cell Function in TODAY
Publicado: (2013)

Pediatric diabetic retinopathy: experience of a tertiary hospital in Ethiopia
por: Shibeshi, Mulugeta Sitot, et al.
Publicado: (2016)

Impact of ATM and SLC22A1 Polymorphisms on Therapeutic Response to Metformin in Iranian Diabetic Patients
por: Shokri, Fazlollah, et al.
Publicado: (2016)

Interaction of rs316019 variants of SLC22A2 with metformin and other drugs- an in silico analysis
por: Sajib, Abu Ashfaqur, et al.
Publicado: (2018)

Pharmacogenetic variation of SLC47A1 gene and metformin response in type2 diabetes patients
por: Mousavi, Saeedeh, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6766g9tfpta6u8nldrblb8s8hp