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Knock-out of the critical nitric oxide synthase regulator DDAH1 in mice impacts amphetamine sensitivity and dopamine metabolism

The enzyme dimethylarginine dimethylaminohydrolase 1 (DDAH1) plays a pivotal role in the regulation of nitric oxide levels by degrading the main endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA). Growing evidence highlight the potential implication of DDAH/ADMA axis in th...

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Detalles Bibliográficos
Autores principales:	Kozlova, Alena A., Rubets, Elena, Vareltzoglou, Magdalini R., Jarzebska, Natalia, Ragavan, Vinitha N., Chen, Yingjie, Martens-Lobenhoffer, Jens, Bode-Böger, Stefanie M., Gainetdinov, Raul R., Rodionov, Roman N., Bernhardt, Nadine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Vienna 2023
Materias:	Psychiatry and Preclinical Psychiatric Studies - Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460711/ https://www.ncbi.nlm.nih.gov/pubmed/36792833 http://dx.doi.org/10.1007/s00702-023-02597-7

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