NCX1 disturbs calcium homeostasis and promotes RANKL-induced osteoclast differentiation by regulating JNK/c-Fos/NFATc1 signaling pathway in multiple myeloma

Although several types of calcium channels abnormalities have been shown to promote myeloma bone disease (MBD), the relationship between Na(+)/Ca(2+) exchanger 1 (NCX1) and MBD remains unexplored. Here, we examined the role of NCX1 in the development of multiple myeloma (MM), with a special focus on...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Qiu, Dongbiao, Chen, Qingjiao, Yang, Apeng, Chen, Junmin, Zeng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460717/
https://www.ncbi.nlm.nih.gov/pubmed/36251145
http://dx.doi.org/10.1007/s10238-022-00905-1

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