Reduction of Intracellular Tension and Cell Adhesion Promotes Open Chromatin Structure and Enhances Cell Reprogramming

The role of transcription factors and biomolecules in cell type conversion has been widely studied. Yet, it remains unclear whether and how intracellular mechanotransduction through focal adhesions (FAs) and the cytoskeleton regulates the epigenetic state and cell reprogramming. Here, it is shown th...

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Detalles Bibliográficos
Autores principales: Soto, Jennifer, Song, Yang, Wu, Yifan, Chen, Binru, Park, Hyungju, Akhtar, Navied, Wang, Peng‐Yuan, Hoffman, Tyler, Ly, Chau, Sia, Junren, Wong, SzeYue, Kelkhoff, Douglas O., Chu, Julia, Poo, Mu‐Ming, Downing, Timothy L., Rowat, Amy C., Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460843/
https://www.ncbi.nlm.nih.gov/pubmed/37357983
http://dx.doi.org/10.1002/advs.202300152

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