Cargando…
ANO1‐Mediated Inhibition of Cancer Ferroptosis Confers Immunotherapeutic Resistance through Recruiting Cancer‐Associated Fibroblasts
The application of immunotherapy in gastrointestinal (GI) cancers remains challenging because of the limited response rate and emerging therapeutic resistance. Combining clinical cohorts, multi‐omics study, and functional/molecular experiments, it is found that ANO1 amplification or high‐expression...
Autores principales: | Jiang, Fangli, Jia, Keren, Chen, Yang, Ji, Congcong, Chong, Xiaoyi, Li, Zhongwu, Zhao, Feilong, Bai, Yuezong, Ge, Sai, Gao, Jing, Zhang, Xiaotian, Li, Jian, Shen, Lin, Zhang, Cheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460848/ https://www.ncbi.nlm.nih.gov/pubmed/37341301 http://dx.doi.org/10.1002/advs.202300881 |
Ejemplares similares
-
Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer
por: Zhang, Cheng, et al.
Publicado: (2022) -
Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
por: Achilli, Silvia, et al.
Publicado: (2021) -
The Ferroptosis Molecular Subtype Reveals Characteristics of the Tumor Microenvironment, Immunotherapeutic Response, and Prognosis in Gastric Cancer
por: Xu, Xiao, et al.
Publicado: (2022) -
Characterization of pyruvate metabolism and citric acid cycle patterns predicts response to immunotherapeutic and ferroptosis in gastric cancer
por: Wang, Xu, et al.
Publicado: (2022) -
Trastuzumab Combined with Irinotecan in Patients with HER2-Positive Metastatic Colorectal Cancer: A Phase II Single-Arm Study and Exploratory Biomarker Analysis
por: Xu, Ting, et al.
Publicado: (2023)