Cargando…

Fibulin7 Mediated Pathological Cardiac Remodeling through EGFR Binding and EGFR‐Dependent FAK/AKT Signaling Activation

Adverse remodeling after myocardial infarction (MI) result in heart failure and sudden cardiac death. Fibulin7 (FBLN7) is an adhesion protein excreted into the extracellular matrix that functions in multiple biological processes. However, whether and how FBLN7 affects post‐MI cardiac remodeling rema...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Xuehui, Liu, Lingxin, Liu, Jing, Zhang, Chen, Zhang, Jie, Qi, Yan, Xie, Lin, Zhang, Chunmei, Yao, Guoqing, Bu, Peili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460860/ https://www.ncbi.nlm.nih.gov/pubmed/37344348 http://dx.doi.org/10.1002/advs.202207631

Ejemplares similares

Sirtuin 3 deficiency aggravates angiotensin II‐induced hypertensive cardiac injury by the impairment of lymphangiogenesis
por: Zhang, Chen, et al.
Publicado: (2021)

Abnormally activated OPN/integrin αVβ3/FAK signalling is responsible for EGFR-TKI resistance in EGFR mutant non-small-cell lung cancer
por: Fu, Yulong, et al.
Publicado: (2020)

Lcz696 Alleviates Myocardial Fibrosis After Myocardial Infarction Through the sFRP-1/Wnt/β-Catenin Signaling Pathway
por: Liu, Jing, et al.
Publicado: (2021)

JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation
por: Zhang, Bo, et al.
Publicado: (2021)

Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3
por: Zhang, Chunmei, et al.
Publicado: (2021)

An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer
por: Tai, Yu-Ling, et al.
Publicado: (2015)

Tongxinluo May Alleviate Inflammation and Improve the Stability of Atherosclerotic Plaques by Changing the Intestinal Flora
por: Qi, Yan, et al.
Publicado: (2022)

Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?
por: Lau, Justine Y., et al.
Publicado: (2010)

Roles of Fibulin-2 in Carcinogenesis
por: Zhang, Huayue, et al.
Publicado: (2020)

Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling
por: Sugiyama, Michael G., et al.
Publicado: (2023)

Expanding the Therapeutic Window of EGFR-Targeted PE24 Immunotoxin for EGFR-Overexpressing Cancers by Tailoring the EGFR Binding Affinity
por: Jun, Sei-Yong, et al.
Publicado: (2022)

EGFR Suppression Inhibits the Sphere Formation of MCF7 Cells Overexpressing EGFR
por: Novak, D. D., et al.
Publicado: (2023)

The role of adhesion protein Fibulin7 in development and diseases
por: Chakraborty, Papiya, et al.
Publicado: (2020)

Trimetazidine ameliorates sunitinib-induced cardiotoxicity in mice via the AMPK/mTOR/autophagy pathway
por: Yang, Yi, et al.
Publicado: (2019)

CD73 promotes cervical cancer growth via EGFR/AKT1 pathway
por: Liu, Chong, et al.
Publicado: (2022)

Arecoline Promotes Migration of A549 Lung Cancer Cells through Activating the EGFR/Src/FAK Pathway
por: Chang, Chih-Hsiang, et al.
Publicado: (2019)

Prognostic value of EGFR and p-EGFR in nasopharyngeal carcinoma: A systematic review and meta-analysis
por: Hong, Xiaohua, et al.
Publicado: (2022)

Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy
por: Chen, Leying, et al.
Publicado: (2022)

Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth
por: Yao, Nan, et al.
Publicado: (2020)

Combination of EGFR-TKIs with chemotherapy versus chemotherapy or EGFR-TKIs alone in advanced NSCLC patients with EGFR mutation
por: Wen, Miaomiao, et al.
Publicado: (2018)

EGFR-specific CAR-T cells trigger cell lysis in EGFR-positive TNBC
por: Liu, Yan, et al.
Publicado: (2019)

Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance
por: Chang, Kwang-Yu, et al.
Publicado: (2013)

TNK2 promoted esophageal cancer progression via activating egfr‐akt signaling
por: Zhang, Anqing, et al.
Publicado: (2021)

Critical roles for EGFR and EGFR–HER2 clusters in EGF binding of SW620 human carcinoma cells
por: Wollman, Adam J. M., et al.
Publicado: (2022)

Targeting TF-AKT/ERK-EGFR Pathway Suppresses the Growth of Hepatocellular Carcinoma
por: Huang, Shan-Zhou, et al.
Publicado: (2019)

Protein Tyrosine Kinase 7 Regulates EGFR/Akt Signaling Pathway and Correlates With Malignant Progression in Triple-Negative Breast Cancer
por: Cui, Nai-Peng, et al.
Publicado: (2021)

A Miniaturized Ligand Binding Assay for EGFR
por: Schwenk, Jochen M., et al.
Publicado: (2012)

Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode
por: Hu, Chen, et al.
Publicado: (2017)

Decrease of Fibulin-3 in Hepatocellular Carcinoma Indicates Poor Prognosis
por: Luo, Rongzhen, et al.
Publicado: (2013)

EGFR-TKIs resistance via EGFR-independent signaling pathways
por: Liu, Qian, et al.
Publicado: (2018)

ADAM23 in Cardiomyocyte Inhibits Cardiac Hypertrophy by Targeting FAK‐AKT Signaling
por: Xiang, Mei, et al.
Publicado: (2018)

EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis
por: Zhang, Xuedi, et al.
Publicado: (2022)

Clinical and Pathological Features of Chinese Patients with Type 2 Diabetes, Biopsy-Proven Diabetic Kidney Disease, and Rapid eGFR Decline
por: Qin, Chunmei, et al.
Publicado: (2022)

EGFR-AS1 Promotes Bladder Cancer Progression by Upregulating EGFR
por: Wang, Anbang, et al.
Publicado: (2020)

Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation
por: Wang, Aoli, et al.
Publicado: (2016)

Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways
por: Zhao, Jun, et al.
Publicado: (2022)

Fibulin-5 for youthful skin
por: Williams, Ruth
Publicado: (2007)

The Pathophysiological Significance of Fibulin-3
por: Livingstone, Imogen, et al.
Publicado: (2020)

Fibulin-4 and -5, but not Fibulin-2, are Associated with Tropoelastin Deposition in Elastin-Producing Cell Culture
por: Yamauchi, Yoshinori, et al.
Publicado: (2010)

Correlations between EGFR gene polymorphisms and pleural metastasis of lung adenocarcinoma
por: Guo, Haisheng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7j6c79fml64n0coq0o5kqooaji