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Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023)

Cancer Reversion A genetic alteration can disrupt input‐output relationship of the intracellular regulatory network within a cancer cell. However, by making use of the inherent redundancy remained in the complex network, we can still restore the input‐output relationship through regulation of a prop...

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Detalles Bibliográficos
Autores principales: Joo, Jae Il, Park, Hwa‐Jeong, Cho, Kwang‐Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460868/
http://dx.doi.org/10.1002/advs.202370164
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author Joo, Jae Il
Park, Hwa‐Jeong
Cho, Kwang‐Hyun
author_facet Joo, Jae Il
Park, Hwa‐Jeong
Cho, Kwang‐Hyun
author_sort Joo, Jae Il
collection PubMed
description Cancer Reversion A genetic alteration can disrupt input‐output relationship of the intracellular regulatory network within a cancer cell. However, by making use of the inherent redundancy remained in the complex network, we can still restore the input‐output relationship through regulation of a proper molecular target and induce cancer reversion. More details can be found in article number 2207322 by Jae Il Joo, Hwa‐Jeong Park, and Kwang‐Hyun Cho. [Image: see text]
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spelling pubmed-104608682023-08-29 Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023) Joo, Jae Il Park, Hwa‐Jeong Cho, Kwang‐Hyun Adv Sci (Weinh) Inside Back Cover Cancer Reversion A genetic alteration can disrupt input‐output relationship of the intracellular regulatory network within a cancer cell. However, by making use of the inherent redundancy remained in the complex network, we can still restore the input‐output relationship through regulation of a proper molecular target and induce cancer reversion. More details can be found in article number 2207322 by Jae Il Joo, Hwa‐Jeong Park, and Kwang‐Hyun Cho. [Image: see text] John Wiley and Sons Inc. 2023-08-27 /pmc/articles/PMC10460868/ http://dx.doi.org/10.1002/advs.202370164 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Back Cover
Joo, Jae Il
Park, Hwa‐Jeong
Cho, Kwang‐Hyun
Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023)
title Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023)
title_full Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023)
title_fullStr Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023)
title_full_unstemmed Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023)
title_short Normalizing Input–Output Relationships of Cancer Networks for Reversion Therapy (Adv. Sci. 24/2023)
title_sort normalizing input–output relationships of cancer networks for reversion therapy (adv. sci. 24/2023)
topic Inside Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460868/
http://dx.doi.org/10.1002/advs.202370164
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