Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023)

3D Fibrillar Fibronectin In article number 2300812, Seungkuk Ahn, Nico Strohmeyer, Daniel J. Muller, and co‐workers report a simple and easily‐adaptable method to engineer 3D fibrillar fibronectin matrices mimicking native fibrillar tissues. Fibroblasts sense and respond to the biomimetic 3D fibrill...

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Autores principales: Ahn, Seungkuk, Sharma, Upnishad, Kasuba, Krishna Chaitanya, Strohmeyer, Nico, Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460894/
http://dx.doi.org/10.1002/advs.202370163
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author Ahn, Seungkuk
Sharma, Upnishad
Kasuba, Krishna Chaitanya
Strohmeyer, Nico
Müller, Daniel J.
author_facet Ahn, Seungkuk
Sharma, Upnishad
Kasuba, Krishna Chaitanya
Strohmeyer, Nico
Müller, Daniel J.
author_sort Ahn, Seungkuk
collection PubMed
description 3D Fibrillar Fibronectin In article number 2300812, Seungkuk Ahn, Nico Strohmeyer, Daniel J. Muller, and co‐workers report a simple and easily‐adaptable method to engineer 3D fibrillar fibronectin matrices mimicking native fibrillar tissues. Fibroblasts sense and respond to the biomimetic 3D fibrillar matrices via α5β1 integrin and syndecan‐4, which crosstalk to accelerate adhesion within seconds. This rapid fibrillar sensing guides cell growth, migration, and proliferation as depicted in the frontispiece. [Image: see text]
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spelling pubmed-104608942023-08-29 Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023) Ahn, Seungkuk Sharma, Upnishad Kasuba, Krishna Chaitanya Strohmeyer, Nico Müller, Daniel J. Adv Sci (Weinh) Frontispiece 3D Fibrillar Fibronectin In article number 2300812, Seungkuk Ahn, Nico Strohmeyer, Daniel J. Muller, and co‐workers report a simple and easily‐adaptable method to engineer 3D fibrillar fibronectin matrices mimicking native fibrillar tissues. Fibroblasts sense and respond to the biomimetic 3D fibrillar matrices via α5β1 integrin and syndecan‐4, which crosstalk to accelerate adhesion within seconds. This rapid fibrillar sensing guides cell growth, migration, and proliferation as depicted in the frontispiece. [Image: see text] John Wiley and Sons Inc. 2023-08-27 /pmc/articles/PMC10460894/ http://dx.doi.org/10.1002/advs.202370163 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Frontispiece
Ahn, Seungkuk
Sharma, Upnishad
Kasuba, Krishna Chaitanya
Strohmeyer, Nico
Müller, Daniel J.
Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023)
title Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023)
title_full Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023)
title_fullStr Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023)
title_full_unstemmed Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023)
title_short Engineered Biomimetic Fibrillar Fibronectin Matrices Regulate Cell Adhesion Initiation, Migration, and Proliferation via α5β1 Integrin and Syndecan‐4 Crosstalk (Adv. Sci. 24/2023)
title_sort engineered biomimetic fibrillar fibronectin matrices regulate cell adhesion initiation, migration, and proliferation via α5β1 integrin and syndecan‐4 crosstalk (adv. sci. 24/2023)
topic Frontispiece
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460894/
http://dx.doi.org/10.1002/advs.202370163
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