Cargando…

Genetic architecture and polygenic risk score prediction of degenerative suspensory ligament desmitis (DSLD) in the Peruvian Horse

Introduction: Spontaneous rupture of tendons and ligaments is common in several species including humans. In horses, degenerative suspensory ligament desmitis (DSLD) is an important acquired idiopathic disease of a major energy-storing tendon-like structure. DSLD risk is increased in several breeds,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Momen, Mehdi, Brauer, Kiley, Patterson, Margaret M., Sample, Susannah J., Binversie, Emily E., Davis, Brian W., Cothran, E. Gus, Rosa, Guilherme J. M., Brounts, Sabrina H., Muir, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460910/ https://www.ncbi.nlm.nih.gov/pubmed/37645058 http://dx.doi.org/10.3389/fgene.2023.1201628

Ejemplares similares

Degenerative Suspensory Ligament Desmitis (DSLD) in Peruvian Paso Horses Is Characterized by Altered Expression of TGFβ Signaling Components in Adipose-Derived Stromal Fibroblasts
por: Luo, Wei, et al.
Publicado: (2016)

Selection signature analyses and genome‐wide association reveal genomic hotspot regions that reflect differences between breeds of horse with contrasting risk of degenerative suspensory ligament desmitis
por: Momen, Mehdi, et al.
Publicado: (2022)

Differential gene expression in skin RNA of horses affected with degenerative suspensory ligament desmitis
por: Haythorn, Abigail, et al.
Publicado: (2020)

Degenerative suspensory ligament desmitis as a systemic disorder characterized by proteoglycan accumulation
por: Halper, Jaroslava, et al.
Publicado: (2006)

Does BMP2 play a role in the pathogenesis of equine degenerative suspensory ligament desmitis?
por: Young, Madeline, et al.
Publicado: (2018)

Tenogenically Induced Allogeneic Mesenchymal Stem Cells for the Treatment of Proximal Suspensory Ligament Desmitis in a Horse
por: Vandenberghe, Aurélie, et al.
Publicado: (2015)

Onchocerca sp. in an imported Zangersheide gelding causing suspensory ligament desmitis
por: Brown, Kara A., et al.
Publicado: (2023)

Ultrasonic debridement with stem cell therapy of suspensory branch desmitis in an equine patient
por: Kamineni, Srinath, et al.
Publicado: (2019)

Expression of genes with biomarker potential identified in skin from DSLD-affected horses increases with age
por: Roberts, Jennifer Hope, et al.
Publicado: (2023)

Heritability and genetic variance estimation of Osteosarcoma (OSA) in Irish Wolfhound, using deep pedigree information
por: Momen, Mehdi, et al.
Publicado: (2021)

Biologically Enhanced Genome-Wide Association Study Provides Further Evidence for Candidate Loci and Discovers Novel Loci That Influence Risk of Anterior Cruciate Ligament Rupture in a Dog Model
por: Baker, Lauren A., et al.
Publicado: (2021)

Identification of genetic variants associated with anterior cruciate ligament rupture and AKC standard coat color in the Labrador Retriever
por: Lee, BT, et al.
Publicado: (2023)

Genetic variability in the Skyros pony and its relationship with other Greek and foreign horse breeds
por: Bömcke, Elisabeth, et al.
Publicado: (2011)

Maternal phylogenetic relationships and genetic variation among Arabian horse populations using whole mitochondrial DNA D-loop sequencing
por: Khanshour, Anas M, et al.
Publicado: (2013)

Bayesian and Machine Learning Models for Genomic Prediction of Anterior Cruciate Ligament Rupture in the Canine Model
por: Baker, Lauren A., et al.
Publicado: (2020)

A Suspensory
por: Wilkerson, Basil M.
Publicado: (1880)

Subclinical Ultrasonographic Abnormalities of the Suspensory Ligament Branches Are Common in Elite Showjumping Warmblood Horses
por: Read, Rachel Mercedes, et al.
Publicado: (2020)

A missense mutation in PMEL17 is associated with the Silver coat color in the horse
por: Brunberg, Emma, et al.
Publicado: (2006)

Gene Therapy Using Plasmid DNA Encoding VEGF164 and FGF2 Genes: A Novel Treatment of Naturally Occurring Tendinitis and Desmitis in Horses
por: Kovac, Milomir, et al.
Publicado: (2018)

Multivariate genome-wide association analysis identifies novel and relevant variants associated with anterior cruciate ligament rupture risk in the dog model
por: Baker, Lauren A., et al.
Publicado: (2018)

Identification of copy number variants in horses
por: Doan, Ryan, et al.
Publicado: (2012)

Late‐onset laryngeal paralysis: Owner perception of quality of life and cause of death
por: Sample, Susannah J., et al.
Publicado: (2020)

Genetic diversity and origin of the feral horses in Theodore Roosevelt National Park
por: Ovchinnikov, Igor V., et al.
Publicado: (2018)

Analysis of copy number variation in dogs implicates genomic structural variation in the development of anterior cruciate ligament rupture
por: Binversie, Emily E., et al.
Publicado: (2020)

Copy number variation of horse Y chromosome genes in normal equine populations and in horses with abnormal sex development and subfertility: relationship of copy number variations with Y haplogroups
por: Castaneda, Caitlin, et al.
Publicado: (2022)

Axial osteitis of the proximal sesamoid bones and desmitis of the intersesamoidean ligament in the hindlimb of Friesian horses: review of 12 cases (2002-2012) and post-mortem analysis of the bone-ligament interface
por: Brommer, Harold, et al.
Publicado: (2014)

Gene Therapy Using Plasmid DNA Encoding Vascular Endothelial Growth Factor 164 and Fibroblast Growth Factor 2 Genes for the Treatment of Horse Tendinitis and Desmitis: Case Reports
por: Kovac, Milomir, et al.
Publicado: (2017)

Equine Multiple Congenital Ocular Anomalies maps to a 4.9 megabase interval on horse chromosome 6
por: Andersson, Lisa S, et al.
Publicado: (2008)

Across-breed genetic investigation of canine hip dysplasia, elbow dysplasia, and anterior cruciate ligament rupture using whole-genome sequencing
por: Binversie, Emily E., et al.
Publicado: (2022)

From a Single Penile Suspensory Ligament to a Penile Suspensory Apparatus: Application to the Buried Penis Surgery
por: Laurent, Romain, et al.
Publicado: (2023)

Outcome following local injection of a liquid amnion allograft for treatment of equine tendonitis or desmitis – 100 cases
por: Duddy, Hugh. R., et al.
Publicado: (2022)

All-Suture Suspensory Button Has Similar Biomechanical Performance to Metal Suspensory Button for Onlay Subpectoral Biceps Tenodesis
por: Colantonio, Donald F., et al.
Publicado: (2022)

Copy Number Variation in the Horse Genome
por: Ghosh, Sharmila, et al.
Publicado: (2014)

The influence of the metacarpophalangeal joint angle on the transversal area and mean echogenicity of the superficial digital flexor tendon and suspensory ligament in gaited horses
por: SCHADE, Jackson, et al.
Publicado: (2021)

Triple disruption of the superior shoulder suspensory complex
por: Kim, Sae Hoon, et al.
Publicado: (2012)

Are suspensory ligaments important for middle ear reconstruction?
por: Brister, Eileen Y., et al.
Publicado: (2021)

Population Genetic Analysis of the Estonian Native Horse Suggests Diverse and Distinct Genetics, Ancient Origin and Contribution from Unique Patrilines
por: Castaneda, Caitlin, et al.
Publicado: (2019)

Ultrasound Morphometry and Mean Echogenicity of Digital Flexor Tendons, Suspensory Ligament, and Accessory Ligament of Digital Deep Flexor Tendon in Gaited Horses
por: Schade, Jackson, et al.
Publicado: (2023)

European Domestic Horses Originated in Two Holocene Refugia
por: Warmuth, Vera, et al.
Publicado: (2011)

Use of standing low-field magnetic resonance imaging to assess oblique distal sesamoidean ligament desmitis in three Thoroughbred racehorses
por: MIZOBE, Fumiaki, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_oqcdcndt3lf9nernfbf742lhp1