Cargando…

Multicentric Reticulohistiocytosis–A rare and disabling disease

Multicentric reticulohistiocytosis is a rare multisystemic condition associated with papulonodular skin lesions, severe arthritis and malignancy. Histopathology shows histiocytes containing abundant eosinophilic ground glass cytoplasm and multinucleated giant cells. Early recognition, age‐appropriat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashaolu, Omowunmi, Ng, Selwyn, Smale, Shaun, Hughes, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460929/
https://www.ncbi.nlm.nih.gov/pubmed/37645054
http://dx.doi.org/10.1002/ccr3.7846
Descripción
Sumario:Multicentric reticulohistiocytosis is a rare multisystemic condition associated with papulonodular skin lesions, severe arthritis and malignancy. Histopathology shows histiocytes containing abundant eosinophilic ground glass cytoplasm and multinucleated giant cells. Early recognition, age‐appropriate malignancy work‐up and treatment is important to prevent impairment of daily life activity.