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Lorlatinib Tolerability and Association With Clinical Outcomes in Patients With Advanced ALK- or ROS1-Rearranged NSCLC: A Brief Report

INTRODUCTION: Treatment with lorlatinib for patients with advanced ALK- and ROS1-rearranged NSCLC (ALK+ and ROS1+ NSCLC) is associated with a unique set of adverse events (AEs) often requiring dose reduction. However, the impact of dose reductions on outcomes remains unclear and is mainly limited to...

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Detalles Bibliográficos
Autores principales: Thummalapalli, Rohit, Choudhury, Noura J., Ehrich, Fiona, Beardslee, Tyler, Brazel, Danielle, Zhang, Shannon S., Merchant, Shelby, Chen, Monica F., Heller, Glenn, Ramalingam, Suresh S., Ou, Sai-Hong Ignatius, Mileham, Kathryn F., Riely, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460990/
https://www.ncbi.nlm.nih.gov/pubmed/37644967
http://dx.doi.org/10.1016/j.jtocrr.2023.100546