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Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review

A 14-year-old child was diagnosed with complex regional pain syndrome (CRPS) after bromhidrosis surgery. She experienced a stinging, knife-like, and intermittent attack pain, accompanied by numbness of both upper limbs and limited movements. Ultrasound-guided radiofrequency surgery on the peripheral...

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Autores principales: Su, Yaping, Li, Zhenyu, Wang, Qian, Tang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461082/
https://www.ncbi.nlm.nih.gov/pubmed/37645606
http://dx.doi.org/10.3389/fneur.2023.1232199
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author Su, Yaping
Li, Zhenyu
Wang, Qian
Tang, Hui
author_facet Su, Yaping
Li, Zhenyu
Wang, Qian
Tang, Hui
author_sort Su, Yaping
collection PubMed
description A 14-year-old child was diagnosed with complex regional pain syndrome (CRPS) after bromhidrosis surgery. She experienced a stinging, knife-like, and intermittent attack pain, accompanied by numbness of both upper limbs and limited movements. Ultrasound-guided radiofrequency surgery on the peripheral nerve did not reduce pain. Then, gabapentin 300 mg three times a day and 2% lidocaine by local subcutaneous injection once a day for 3 days were administrated. After the local subcutaneous injection of lidocaine, the pain was significantly relieved, and the pain induced by skin touch at the scar disappeared. No pain recurred after the 1-month follow-up. An evidence-based literature review showed that local or systemic intravenous lidocaine was used to reduce adult CRPS symptoms but less has been reported in children. In our case, a local subcutaneous injection of 2% lidocaine in a child for CRPS treatment was reported to be effective in relieving complex local pain with favorable outcomes. Though further high-quality randomized controlled trials are needed to investigate the effects and safety of local subcutaneous lidocaine injection on pain relief in children with CRPS, it could still provide a relatively safe and effective adjuvant therapy for minor patients.
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spelling pubmed-104610822023-08-29 Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review Su, Yaping Li, Zhenyu Wang, Qian Tang, Hui Front Neurol Neurology A 14-year-old child was diagnosed with complex regional pain syndrome (CRPS) after bromhidrosis surgery. She experienced a stinging, knife-like, and intermittent attack pain, accompanied by numbness of both upper limbs and limited movements. Ultrasound-guided radiofrequency surgery on the peripheral nerve did not reduce pain. Then, gabapentin 300 mg three times a day and 2% lidocaine by local subcutaneous injection once a day for 3 days were administrated. After the local subcutaneous injection of lidocaine, the pain was significantly relieved, and the pain induced by skin touch at the scar disappeared. No pain recurred after the 1-month follow-up. An evidence-based literature review showed that local or systemic intravenous lidocaine was used to reduce adult CRPS symptoms but less has been reported in children. In our case, a local subcutaneous injection of 2% lidocaine in a child for CRPS treatment was reported to be effective in relieving complex local pain with favorable outcomes. Though further high-quality randomized controlled trials are needed to investigate the effects and safety of local subcutaneous lidocaine injection on pain relief in children with CRPS, it could still provide a relatively safe and effective adjuvant therapy for minor patients. Frontiers Media S.A. 2023-08-14 /pmc/articles/PMC10461082/ /pubmed/37645606 http://dx.doi.org/10.3389/fneur.2023.1232199 Text en Copyright © 2023 Su, Li, Wang and Tang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Su, Yaping
Li, Zhenyu
Wang, Qian
Tang, Hui
Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review
title Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review
title_full Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review
title_fullStr Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review
title_full_unstemmed Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review
title_short Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review
title_sort local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461082/
https://www.ncbi.nlm.nih.gov/pubmed/37645606
http://dx.doi.org/10.3389/fneur.2023.1232199
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