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Broad-spectrum humanized monoclonal neutralizing antibody against SARS-CoV-2 variants, including the Omicron variant

INTRODUCTION: Therapeutic monoclonal antibodies (mAbs) against the SARS-CoV-2 spike protein have been shown to improve the outcome of severe COVID-19 patients in clinical trials. However, novel variants with spike protein mutations can render many currently available mAbs ineffective. METHODS: We pr...

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Detalles Bibliográficos
Autores principales:	Wen, Kun, Cai, Jian-Piao, Fan, Xiaodi, Zhang, Xiaojuan, Luo, Cuiting, Tang, Kai-Ming, Shuai, Huiping, Chen, Lin-Lei, Zhang, Ricky Ruiqi, Situ, Jianwen, Tsoi, Hoi-Wah, Wang, Kun, Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Yuen, Kwok-Yung, Zhou, Hongwei, To, Kelvin Kai-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461085/ https://www.ncbi.nlm.nih.gov/pubmed/37645378 http://dx.doi.org/10.3389/fcimb.2023.1213806

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