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Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome

Parkinson's disease (PD) is a common neurodegenerative disorder. Some patients with advanced-stage disease are accompanied by emergencies and critical issues such as dyskinesia-hyperpyrexia syndrome (DHS), parkinsonism-hyperpyrexia syndrome (PHS), and serotonin syndrome (SS). In this study, we...

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Detalles Bibliográficos
Autores principales: Luo, Bohan, Zhang, Hainan, Qin, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461438/
https://www.ncbi.nlm.nih.gov/pubmed/37645603
http://dx.doi.org/10.3389/fneur.2023.1234974
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author Luo, Bohan
Zhang, Hainan
Qin, Lixia
author_facet Luo, Bohan
Zhang, Hainan
Qin, Lixia
author_sort Luo, Bohan
collection PubMed
description Parkinson's disease (PD) is a common neurodegenerative disorder. Some patients with advanced-stage disease are accompanied by emergencies and critical issues such as dyskinesia-hyperpyrexia syndrome (DHS), parkinsonism-hyperpyrexia syndrome (PHS), and serotonin syndrome (SS). In this study, we report a patient with reversible encephalopathy caused by DHS who presented with an acute onset of fidgetiness, dyskinesia, and hyperpyrexia after antiparkinsonian drug abuse. In the present case, brain magnetic resonance imaging (MRI) showed multiple abnormal signals in the cortex and subcortex of the bilateral parietal and occipital lobes that resolved within weeks, which coincided with the characteristic MRI findings in posterior reversible encephalopathy (PRES). Our report expands on the neuroimaging features of DHS and highlights the importance of early identification, diagnosis, and treatment to improve patient prognosis.
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spelling pubmed-104614382023-08-29 Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome Luo, Bohan Zhang, Hainan Qin, Lixia Front Neurol Neurology Parkinson's disease (PD) is a common neurodegenerative disorder. Some patients with advanced-stage disease are accompanied by emergencies and critical issues such as dyskinesia-hyperpyrexia syndrome (DHS), parkinsonism-hyperpyrexia syndrome (PHS), and serotonin syndrome (SS). In this study, we report a patient with reversible encephalopathy caused by DHS who presented with an acute onset of fidgetiness, dyskinesia, and hyperpyrexia after antiparkinsonian drug abuse. In the present case, brain magnetic resonance imaging (MRI) showed multiple abnormal signals in the cortex and subcortex of the bilateral parietal and occipital lobes that resolved within weeks, which coincided with the characteristic MRI findings in posterior reversible encephalopathy (PRES). Our report expands on the neuroimaging features of DHS and highlights the importance of early identification, diagnosis, and treatment to improve patient prognosis. Frontiers Media S.A. 2023-08-14 /pmc/articles/PMC10461438/ /pubmed/37645603 http://dx.doi.org/10.3389/fneur.2023.1234974 Text en Copyright © 2023 Luo, Zhang and Qin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Luo, Bohan
Zhang, Hainan
Qin, Lixia
Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_full Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_fullStr Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_full_unstemmed Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_short Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_sort case report: reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461438/
https://www.ncbi.nlm.nih.gov/pubmed/37645603
http://dx.doi.org/10.3389/fneur.2023.1234974
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