Gpr18 agonist dampens inflammation, enhances myogenesis, and restores muscle function in models of Duchenne muscular dystrophy

Introduction: Muscle wasting in Duchenne Muscular Dystrophy is caused by myofiber fragility and poor regeneration that lead to chronic inflammation and muscle replacement by fibrofatty tissue. Our recent findings demonstrated that Resolvin-D2, a bioactive lipid derived from omega-3 fatty acids, has...

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Detalles Bibliográficos
Autores principales: Dort, Junio, Orfi, Zakaria, Fiscaletti, Melissa, Campeau, Philippe M., Dumont, Nicolas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461444/
https://www.ncbi.nlm.nih.gov/pubmed/37645248
http://dx.doi.org/10.3389/fcell.2023.1187253

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