Unique epitope–antibody interactions in the intrinsically disordered proteoglycan-like domain of human carbonic anhydrase IX defined by high-resolution NMR combined with yeast surface display

Carbonic anhydrase (CA)-IX is an extracellular enzyme that is essential in the adaptation of tumor cells to their increasingly more hypoxic and acidic microenvironment. Within the family of carbonic anhydrases, CA-IX is unique in that it is the only CA with an N-terminal intrinsically disordered reg...

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Detalles Bibliográficos
Autores principales: Ni, Feng, Wu, Cunle, Xu, Ping, Wang, Ping, Fortin, Yves, Arbour, Melanie, Masson, Luke, L’Abbé, Denis, Acel, Andrea, Gosselin, Mylene, Lenferink, Anne E.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461516/
https://www.ncbi.nlm.nih.gov/pubmed/37622732
http://dx.doi.org/10.1080/19420862.2023.2248672

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