Tormentic acid, a triterpenoid isolated from the fruits of Chaenomeles speciose, protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway

CONTEXT: Tormentic acid (TA), an effective triterpenoid isolated from Chaenomeles speciosa (Sweet) Nakai (Rosaceae) fruits, exerts an effective treatment for gastric damage. OBJECTIVE: To investigate the gastroprotective effect of TA on indomethacin (IND) damaged GES-1 cells and rats, and explore po...

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Detalles Bibliográficos
Autores principales: He, Jun-Yu, Li, Jie, Zhang, Yuan-Yuan, He, Hai-Bo, He, Yu-Min, Xu, Dao-Xiang, Wang, Xiao, Wu, Hao-Yang, Zhang, Ji-Hong, Jahid, Hasan, Sadia, Akter, Yu, Hui-Fan, Wang, Jun-Zhi, Zou, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461523/
https://www.ncbi.nlm.nih.gov/pubmed/37623313
http://dx.doi.org/10.1080/13880209.2023.2249526

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