Cargando…

The Bovine Ex Vivo Retina: A Versatile Model for Retinal Neuroscience

PURPOSE: The isolated ex vivo retina is the standard model in retinal physiology and neuroscience. During isolation, the retina is peeled from the retinal pigment epithelium (RPE), which plays a key role in the visual cycle. Here we introduce the choroid-attached bovine retina as an in vivo–like mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kralik, Jakub, van Wyk, Michiel, Leonardon, Benjamin, Schilardi, Giulia, Schneider, Sabine, Kleinlogel, Sonja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Visual Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461644/ https://www.ncbi.nlm.nih.gov/pubmed/37610761 http://dx.doi.org/10.1167/iovs.64.11.29

Ejemplares similares

Selective Block of Upregulated Kv1.3 Potassium Channels in ON-Bipolar Cells of the Blind Retina Enhances Optogenetically Restored Signaling
por: Schilardi, Giulia, et al.
Publicado: (2023)

Bipolar cell targeted optogenetic gene therapy restores parallel retinal signaling and high-level vision in the degenerated retina
por: Kralik, Jakub, et al.
Publicado: (2022)

Two Functional Classes of Rod Bipolar Cells in the Healthy and Degenerated Optogenetically Treated Murine Retina
por: Schilardi, Giulia, et al.
Publicado: (2022)

Variable phenotypic expressivity in inbred retinal degeneration mouse lines: A comparative study of C3H/HeOu and FVB/N rd1 mice
por: van Wyk, Michiel, et al.
Publicado: (2015)

Functional Availability of ON-Bipolar Cells in the Degenerated Retina: Timing and Longevity of an Optogenetic Gene Therapy
por: Kralik, Jakub, et al.
Publicado: (2021)

Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool
por: van Wyk, Michiel, et al.
Publicado: (2015)

Expression and Localization of Kcne2 in the Vertebrate Retina
por: Lindner, Moritz, et al.
Publicado: (2020)

Composition of the Inner Nuclear Layer in Human Retina
por: Masri, Rania A., et al.
Publicado: (2021)

A visual opsin from jellyfish enables precise temporal control of G protein signalling
por: van Wyk, Michiel, et al.
Publicado: (2023)

Early Functional and Morphologic Abnormalities in the Diabetic Nyx(nob) Mouse Retina
por: Tarchick, Matthew J., et al.
Publicado: (2016)

Correcting QUEST Magnetic Resonance Imaging–Sensitive Free Radical Production in the Outer Retina In Vivo Does Not Correct Reduced Visual Performance in 24-Month-Old C57BL/6J Mice
por: Berkowitz, Bruce A., et al.
Publicado: (2021)

Bipolar Cell Type-Specific Expression and Conductance of Alpha-7 Nicotinic Acetylcholine Receptors in the Mouse Retina
por: Hall, Leo M., et al.
Publicado: (2019)

WNT Activation and TGFβ-Smad Inhibition Potentiate Stemness of Mammalian Auditory Neuroprogenitors for High-Throughput Generation of Functional Auditory Neurons In Vitro
por: Rousset, Francis, et al.
Publicado: (2022)

Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine
por: Bergen, Michael A., et al.
Publicado: (2016)

Ablation of Mature miR-183 Leads to Retinal Dysfunction in Mice
por: Zhang, Chang-Jun, et al.
Publicado: (2020)

Retinal Dopamine D2 Receptors Participate in the Development of Myopia in Mice
por: Huang, Furong, et al.
Publicado: (2022)

Cellular-Level Visualization of Retinal Pathology in Multiple Sclerosis With Adaptive Optics
por: Hammer, Daniel X., et al.
Publicado: (2023)

Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells
por: Moore-Dotson, Johnnie M., et al.
Publicado: (2019)

Ex Vivo Integration of Human Stem Retinal Ganglion Cells into the Mouse Retina
por: Croteau, Louis-Philippe, et al.
Publicado: (2022)

Dopamine Deficiency Mediates Early Rod-Driven Inner Retinal Dysfunction in Diabetic Mice
por: Kim, Moon K., et al.
Publicado: (2018)

Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype
por: Wu, Mengjuan, et al.
Publicado: (2021)

Sonographic Retrobulbar Spot Sign in Diagnosis of Central Retinal Artery Occlusion: A Case Report
por: Usheva, Emiliya, et al.
Publicado: (2023)

Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response
por: Yeh, Connie Y., et al.
Publicado: (2017)

Outer Retinal Assessment Using Spectral-Domain Optical Coherence Tomography in Patients With Alzheimer's and Parkinson's Disease
por: Uchida, Atsuro, et al.
Publicado: (2018)

Orexin-A Suppresses Signal Transmission to Dopaminergic Amacrine Cells From Outer and Inner Retinal Photoreceptors
por: Qiao, Sheng-Nan, et al.
Publicado: (2017)

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells
por: Mead, Ben, et al.
Publicado: (2020)

Early Retinal Neuronal Dysfunction in Diabetic Mice: Reduced Light-Evoked Inhibition Increases Rod Pathway Signaling
por: Moore-Dotson, Johnnie M., et al.
Publicado: (2016)

Columnar and Laminar Segregation of Retinal Input to the Primate Superior Colliculus Revealed by Anterograde Tracer Injection Into Each Eye
por: Dilbeck, Mikayla D., et al.
Publicado: (2022)

Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice
por: Kolesnikov, Alexander V., et al.
Publicado: (2022)

Present Molecular Limitations of ON-Bipolar Cell Targeted Gene Therapy
por: van Wyk, Michiel, et al.
Publicado: (2017)

Analysis of the chicken retina with an adaptive optics multiphoton microscope
por: Bueno, Juan M., et al.
Publicado: (2011)

Amacrine Cells Forming Gap Junctions With Intrinsically Photosensitive Retinal Ganglion Cells: ipRGC Types, Neuromodulator Contents, and Connexin Isoform
por: Harrison, Krystal R., et al.
Publicado: (2021)

Cortical Atrophy Predicts Visual Performance in Long-Term Central Retinal Disease; GCL, pRNFL and Cortical Thickness Are Key Biomarkers
por: Hanson, Rachel L. W., et al.
Publicado: (2022)

Investigation of the Protective Effect of Extracellular Vesicle miR-124 on Retinal Ganglion Cells Using a Photolabile Paper-Based Chip
por: Chen, Yi-Hsun, et al.
Publicado: (2023)

The Pattern of Retinal Ganglion Cell Loss in OPA1-Related Autosomal Dominant Optic Atrophy Inferred From Temporal, Spatial, and Chromatic Sensitivity Losses
por: Majander, Anna, et al.
Publicado: (2017)

Two-photon excited autofluorescence imaging of freshly isolated frog retinas
por: Lu, Rong-Wen, et al.
Publicado: (2011)

Relative Myopic Defocus in the Superior Retina as an Indicator of Myopia Development in Children
por: Lin, Zhenghua, et al.
Publicado: (2023)

Hydroxychloroquine retinal toxicity: The bull's eye in the human eye
por: Au, Sunny, Chi Lik
Publicado: (2020)

Neural Organoids, a Versatile Model for Neuroscience
por: Lee, Ju-Hyun, et al.
Publicado: (2022)

In Vivo Evidence for Impaired Glymphatic Function in the Visual Pathway of Patients With Normal Pressure Hydrocephalus
por: Jacobsen, Henrik Holvin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qas25r6h3encv8keq7o1coc5b5